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Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities

التفاصيل البيبلوغرافية
العنوان: Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities
المؤلفون: Gabriele Carullo, Fabio Sciubba, Paolo Governa, Sarah Mazzotta, Luca Frattaruolo, Giorgio Grillo, Anna Rita Cappello, Giancarlo Cravotto, Maria Enrica Di Cocco, Francesca Aiello
المصدر: Pharmaceuticals, Vol 13, Iss 5, p 97 (2020)
بيانات النشر: MDPI AG, 2020.
سنة النشر: 2020
المجموعة: LCC:Medicine
LCC:Pharmacy and materia medica
مصطلحات موضوعية: Soxhlet, grape seeds, anti-inflammatory, wound healing, lipophilic fraction, carotenoids, Medicine, Pharmacy and materia medica, RS1-441
الوصف: The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable applications such as health-promoting properties are still under investigation. The seeds of the white berries of Mantonico and Pecorello cv. were extracted in a Soxhlet apparatus, using n-hexane and chloroform as solvents. Extracts were characterized by NMR and GC-MS analyses. They were assayed in vitro as wound healing and anti-inflammatory agents in HaCaT and RAW 264.7 cell lines, respectively. n-hexane Mantonico extract resulted in the most interesting wound healing sample, while n-hexane Pecorello, containing a good number of carotenoids, resulted in a good anti-inflammatory candidate. These preliminary findings underlined the benefit of grape seed extracts valorization due to their health-promoting properties.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1424-8247
Relation: https://www.mdpi.com/1424-8247/13/5/97; https://doaj.org/toc/1424-8247
DOI: 10.3390/ph13050097
URL الوصول: https://doaj.org/article/d81428f976cf45d8be9eef0f50541215
رقم الأكسشن: edsdoj.81428f976cf45d8be9eef0f50541215
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14248247
DOI:10.3390/ph13050097