دورية أكاديمية
Pathology of COVID-19: A Review of Emerging Evidences from Autopsy Studies
| العنوان: | Pathology of COVID-19: A Review of Emerging Evidences from Autopsy Studies |
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| المؤلفون: | Seetu Palo, Debadutta Mishra |
| المصدر: | Journal of Clinical and Diagnostic Research, Vol 15, Iss 4, Pp EE01-EE05 (2021) |
| بيانات النشر: | JCDR Research and Publications Private Limited, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | acute tubular injury, coronavirus disease 2019, diffuse alveolar damage, microthrombi, severe acute respiratory syndrome coronavirus-2, Medicine |
| الوصف: | Coronavirus Disease 2019 (COVID‑19) is caused by novel Severe Acute Respiratory Syndrome Coronavirus‑2 (SARS‑CoV‑2). The disease was first reported from Wuhan, China, in December 2019 and since then it continues to spread worldwide. Although, there are rapidly increasing number of studies on epidemiologic characteristics and clinical aspects of COVID-19, its pathology still remains a largely unexplored territory, mainly due to limited autopsy studies. Autopsy studies are essential to demonstrate the spectrum of COVID-19-associated organ changes. This article reviews and highlights the important histopathological findings observed in different organ systems as evident from various published and anecdotal reports from across the world. Major histopathological findings in the lungs include different stages of Diffuse Alveolar Damage (DAD) and microthrombi along with variable degree of inflammation. Microscopic analysis of renal parenchyma may show acute tubular injury and fibrin thrombi in the glomerular capillaries. Heart, liver and brain show no significant inflammatory changes. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2249-782X 0973-709X |
| Relation: | https://www.jcdr.net/articles/PDF/14675/47604_CE[Ra1]_F[SK]_PF1(AKA_SHU)_PN(KM).pdf; https://doaj.org/toc/2249-782X; https://doaj.org/toc/0973-709X |
| DOI: | 10.7860/JCDR/2021/47604.14675 |
| URL الوصول: | https://doaj.org/article/8339445869ca4896bc6995b7dcce3323 |
| رقم الأكسشن: | edsdoj.8339445869ca4896bc6995b7dcce3323 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2249782X 0973709X |
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| DOI: | 10.7860/JCDR/2021/47604.14675 |