دورية أكاديمية

Pretreatment eosinophil counts as a predictive biomarker in non‐small cell lung cancer patients treated with immune checkpoint inhibitors

التفاصيل البيبلوغرافية
العنوان: Pretreatment eosinophil counts as a predictive biomarker in non‐small cell lung cancer patients treated with immune checkpoint inhibitors
المؤلفون: Eiji Takeuchi, Kensuke Kondo, Yoshio Okano, Seiya Ichihara, Michihiro Kunishige, Naoki Kadota, Hisanori Machida, Nobuo Hatakeyama, Keishi Naruse, Hirokazu Ogino, Hiroshi Nokihara, Tsutomu Shinohara, Yasuhiko Nishioka
المصدر: Thoracic Cancer, Vol 14, Iss 30, Pp 3042-3050 (2023)
بيانات النشر: Wiley, 2023.
سنة النشر: 2023
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: biomarker, immune checkpoint inhibitors, non‐small cell lung cancer, predictive factor, pretreatment eosinophils, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Abstract Background The peripheral blood eosinophil count prior to treatment has potential as a predictive biomarker for a beneficial clinical response to cancer immunotherapies. Therefore, the present study investigated the impact of the eosinophil count on overall survival (OS) in non‐small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICI). Methods We retrospectively reviewed all patients diagnosed with NSCLC and treated with ICI monotherapy between March 2016 and August 2021 at National Hospital Organization Kochi Hospital and Tokushima University. Results A total of 166 patients were included. Fifty‐five patients had an eosinophil count of less than 100 cells/μL (Eo
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1759-7714
1759-7706
Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714
DOI: 10.1111/1759-7714.15100
URL الوصول: https://doaj.org/article/83c945d99b1141fba1983672df71bb1f
رقم الأكسشن: edsdoj.83c945d99b1141fba1983672df71bb1f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17597714
17597706
DOI:10.1111/1759-7714.15100