دورية أكاديمية
Pretreatment eosinophil counts as a predictive biomarker in non‐small cell lung cancer patients treated with immune checkpoint inhibitors
العنوان: | Pretreatment eosinophil counts as a predictive biomarker in non‐small cell lung cancer patients treated with immune checkpoint inhibitors |
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المؤلفون: | Eiji Takeuchi, Kensuke Kondo, Yoshio Okano, Seiya Ichihara, Michihiro Kunishige, Naoki Kadota, Hisanori Machida, Nobuo Hatakeyama, Keishi Naruse, Hirokazu Ogino, Hiroshi Nokihara, Tsutomu Shinohara, Yasuhiko Nishioka |
المصدر: | Thoracic Cancer, Vol 14, Iss 30, Pp 3042-3050 (2023) |
بيانات النشر: | Wiley, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | biomarker, immune checkpoint inhibitors, non‐small cell lung cancer, predictive factor, pretreatment eosinophils, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Abstract Background The peripheral blood eosinophil count prior to treatment has potential as a predictive biomarker for a beneficial clinical response to cancer immunotherapies. Therefore, the present study investigated the impact of the eosinophil count on overall survival (OS) in non‐small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICI). Methods We retrospectively reviewed all patients diagnosed with NSCLC and treated with ICI monotherapy between March 2016 and August 2021 at National Hospital Organization Kochi Hospital and Tokushima University. Results A total of 166 patients were included. Fifty‐five patients had an eosinophil count of less than 100 cells/μL (Eo |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1759-7714 1759-7706 |
Relation: | https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714 |
DOI: | 10.1111/1759-7714.15100 |
URL الوصول: | https://doaj.org/article/83c945d99b1141fba1983672df71bb1f |
رقم الأكسشن: | edsdoj.83c945d99b1141fba1983672df71bb1f |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17597714 17597706 |
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DOI: | 10.1111/1759-7714.15100 |