دورية أكاديمية
Vitamin D Supplementation Has No Impact on Cardiorespiratory Fitness, but Improves Inflammatory Status in Vitamin D Deficient Young Men Engaged in Resistance Training
| العنوان: | Vitamin D Supplementation Has No Impact on Cardiorespiratory Fitness, but Improves Inflammatory Status in Vitamin D Deficient Young Men Engaged in Resistance Training |
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| المؤلفون: | Lauri Savolainen, Saima Timpmann, Martin Mooses, Luule Medijainen, Lisette Tõnutare, Frederik Ross, Märt Lellsaar, Anneli Piir, Mihkel Zilmer, Eve Unt, Vahur Ööpik |
| المصدر: | Nutrients, Vol 14, Iss 24, p 5302 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Nutrition. Foods and food supply |
| مصطلحات موضوعية: | vitamin D, cytokines, low-grade inflammation, maximal oxygen consumption, Nutrition. Foods and food supply, TX341-641 |
| الوصف: | Data on the effect of vitamin D (Vit-D) supplementation on cardiorespiratory fitness (VO2max) are conflicting. A possible source of discrepancies in the literature is the heterogeneity in baseline Vit-D status among participants in previous studies. The main objectives of the present study were to assess the impact of Vit-D supplementation on VO2max and inflammatory status in Vit-D deficient young healthy men. Participants (n = 39, baseline serum Vit-D level < 50 nmol/L) were quasi-randomly assigned to one of the two groups, which, in a double-blind manner, supplemented their diet daily with either Vit-D (8000 IU; VD) or placebo (PLC) and concomitantly performed a 12-week supervised resistance training program. During the 12-week intervention, serum Vit-D concentrations increased 3.9-fold (p < 0.001) in the VD group while no changes occurred in the PLC group. Baseline VO2max did not differ in the two groups and remained unchanged during the intervention. Serum interleukin-10/tumour necrosis factor alpha ratio increased significantly (30%, p = 0.007; effect size 0.399) in VD but not in PLC group. In conclusion, 12-week Vit-D supplementation increases serum 25(OH)D levels and improves inflammatory status, but has no impact on VO2max in Vit-D deficient young men engaged in resistance training. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 14245302 2072-6643 |
| Relation: | https://www.mdpi.com/2072-6643/14/24/5302; https://doaj.org/toc/2072-6643 |
| DOI: | 10.3390/nu14245302 |
| URL الوصول: | https://doaj.org/article/86f58fdafb084e958ad72419331d09a6 |
| رقم الأكسشن: | edsdoj.86f58fdafb084e958ad72419331d09a6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14245302 20726643 |
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| DOI: | 10.3390/nu14245302 |