دورية أكاديمية
أعرض في EDS

COVID-19 vaccine short-term adverse events in the real-life family practice in Krakow, Poland

التفاصيل البيبلوغرافية
العنوان: COVID-19 vaccine short-term adverse events in the real-life family practice in Krakow, Poland
المؤلفون: Marek Oleszczyk, Zuzanna Marciniak, Katarzyna Nessler, Ewa Wójtowicz, Nataliya Szozda, Elżbieta Kryj-Radziszewska, Maria Boroń, Klaudia Gajos, Mateusz P. Paziewski, Paweł Sajdak, Adam Windak
المصدر: European Journal of General Practice, Vol 29, Iss 2 (2023)
بيانات النشر: Taylor & Francis Group, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: COVID-19 vaccine, vaccine adverse event, primary care, family medicine, pragmatic study, Medicine (General), R5-920
الوصف: AbstractBackground In manufacturers’ trials, vaccination against COVID-19 proved to be safe and effective. The officially reported frequency of vaccine adverse events (VAEs) in Poland is lower than that declared by the manufacturers. The anti-vaccination activists questioned the trustworthiness of official data.Objectives The aim was to explore the real-life prevalence of VAEs in general practice settings and the factors that may influence it.Methods In this pragmatic, mixed prospective and retrospective study, patients vaccinated against COVID-19 between May and October 2021 in three GP practices in Krakow, Poland, were enrolled. Their demographic (age, sex, level of education) and clinical data (weight and height, smoking status, history of allergies, COVID-19 and chronic diseases) were collected. Then, they were interviewed about VAEs they experienced.Results Out of 1530 patients invited to participate, 1051 (69%) agreed and were eligible for analyses. Only 8.8% did not report any VAE. Pain at the injection site was the most frequently reported reaction (800, 76.2%). The most prevalent systemic ones were excessive fatigue/lethargy (527, 50.6%), sleep/circadian rhythm disturbances (433, 41.6%) and headache (399, 38.3%). Fifty required medical assistance − 39 experienced presyncope (3.7%) and 11 loss of consciousness (1.1%). Only two others were hospitalised. Females, younger adults, those with higher education and with a history of COVID-19 reported systemic VAEs more frequently, while those who were older and obese were less likely to report local reactions.Conclusion Although more than 90% of patients vaccinated against COVID-19 in general practice settings may experience VAEs, in short-term observation, the vast majority are localised and mild.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 13814788
1751-1402
1381-4788
Relation: https://doaj.org/toc/1381-4788; https://doaj.org/toc/1751-1402
DOI: 10.1080/13814788.2022.2147500
URL الوصول: https://doaj.org/article/8765cea31bbe4ba7bdc5eb8ce627f0dd
رقم الأكسشن: edsdoj.8765cea31bbe4ba7bdc5eb8ce627f0dd
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:13814788
17511402
DOI:10.1080/13814788.2022.2147500