دورية أكاديمية

Resveratrol Supplementation Prevents Hypertension in Hypertensive Pregnant Rats by Increasing Sodium Excretion and Serum Nitric Oxide Level

التفاصيل البيبلوغرافية
العنوان: Resveratrol Supplementation Prevents Hypertension in Hypertensive Pregnant Rats by Increasing Sodium Excretion and Serum Nitric Oxide Level
المؤلفون: Xiaowen Jia, Rong Zhang, Jinzhu Guo, Hua Yue, Qiuxia Liu, Lipei Guo, Qunchang Zhang
المصدر: International Journal of Hypertension, Vol 2020 (2020)
بيانات النشر: Wiley, 2020.
سنة النشر: 2020
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Background. Pregnancy-induced hypertension (PIH) remains a major cause of morbidity and mortality in pregnancy worldwide. This study was designed to study the blood pressure-lowering effect of resveratrol (RES) in a salt-induced hypertensive pregnant rat model. Methods. Forty female Sprague Dawley (SD) rats were randomized into 4 groups: Normal Preg (0.9% salt diet), Normal Preg + RES (0.9% salt diet plus daily oral RES for 4 weeks), Salt Preg (8% salt diet), and Salt Preg + RES (8% salt diet plus daily oral RES for 4 weeks). Noninvasive blood pressure was recorded on gestational days 7 and 14. On the gestational day 19, foetuses were weighed, and blood and urine samples were harvested for electrolytes and biochemical assays. Results. RES significantly reduced SBP, DBP, and MAP on gestational days 7 and 14 in the Salt Preg + RES group compared to the Salt Preg group (all P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2090-0384
2090-0392
Relation: https://doaj.org/toc/2090-0384; https://doaj.org/toc/2090-0392
DOI: 10.1155/2020/4154010
URL الوصول: https://doaj.org/article/8b45b6938e3e4391a192d25e7f0b29e6
رقم الأكسشن: edsdoj.8b45b6938e3e4391a192d25e7f0b29e6
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20900384
20900392
DOI:10.1155/2020/4154010