دورية أكاديمية
Residual SARS-CoV-2 RNA in nasal swabs of convalescent COVID-19 patients: Is prolonged quarantine always justified?
العنوان: | Residual SARS-CoV-2 RNA in nasal swabs of convalescent COVID-19 patients: Is prolonged quarantine always justified? |
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المؤلفون: | Antonio Piralla, Matteo Ricchi, Maria Grazia Cusi, Paola Prati, Nadia Vicari, Giada Scarsi, Claudia Gandolfo, Gabriele Anichini, Chiara Terrosi, Elena Percivalle, Edoardo Vecchio Nepita, Federica Bergami, Monica Tallarita, Raffaella Di Martino, Alessandro Ferrari, Francesca Rovida, Giovanna Lunghi, Roberta Schiavo, Fausto Baldanti |
المصدر: | International Journal of Infectious Diseases, Vol 102, Iss , Pp 299-302 (2021) |
بيانات النشر: | Elsevier, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Infectious and parasitic diseases |
مصطلحات موضوعية: | SARS-CoV-2, COVID-19, Virus isolation, Real-time reverse transcription PCR, Cq value, Infectivity, Infectious and parasitic diseases, RC109-216 |
الوصف: | Real-time reverse transcription PCR is currently the most sensitive method to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Defining whether a patient could be contagious or not contagious in the presence of residual SARS-CoV-2 RNA is of extreme importance in the context of public health. In this prospective multicenter study, virus isolation was prospectively attempted in 387 nasal swabs from clinically recovered patients showing low viral load (quantification cycle, Cq, value greater than 30). The median Cq value was 36.8 (range 30.0–39.4). Overall, a cytopathic effect was detected in nine samples, corresponding to a culture positivity rate of 2.3% (9/387). The results of this study help to dissect true virus replication and residual viral RNA detection in recovered patients. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1201-9712 |
Relation: | http://www.sciencedirect.com/science/article/pii/S1201971220322785; https://doaj.org/toc/1201-9712 |
DOI: | 10.1016/j.ijid.2020.10.072 |
URL الوصول: | https://doaj.org/article/8db9e3c000804b30a2f3ea82bc69eb4e |
رقم الأكسشن: | edsdoj.8db9e3c000804b30a2f3ea82bc69eb4e |
قاعدة البيانات: | Directory of Open Access Journals |
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