دورية أكاديمية
Selective Arterial Embolization of Ruptured Hepatocellular Carcinoma with N-Butyl Cyanoacrylate and Lipiodol: Safety, Efficacy, and Short-Term Outcomes
العنوان: | Selective Arterial Embolization of Ruptured Hepatocellular Carcinoma with N-Butyl Cyanoacrylate and Lipiodol: Safety, Efficacy, and Short-Term Outcomes |
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المؤلفون: | Jory Cali, Olivier Chevallier, Kévin Guillen, Marianne Latournerie, Amin Mazit, Ludwig Serge Aho-Glélé, Romaric Loffroy |
المصدر: | Journal of Personalized Medicine, Vol 13, Iss 11, p 1581 (2023) |
بيانات النشر: | MDPI AG, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | hepatocellular carcinoma rupture, embolization, glue, cyanoacrylate, interventional radiology, bleeding control, Medicine |
الوصف: | The rupture of hepatocellular carcinoma (rHCC) is uncommon but causes sudden life-threatening bleeding. Selective transarterial embolization (STAE) is an effective bleeding-control option. The optimal embolic agent is unknown, and data on the use of cyanoacrylate glue are lacking. The objective of this study was to report the outcomes of cyanoacrylate-lipiodol embolization for rHCC. We retrospectively reviewed the files of the 16 patients (14 males; mean age, 72 years) who underwent emergency cyanoacrylate-lipiodol STAE at a single center in 2012–2023 for spontaneous rHCC. All 16 patients had subcapsular HCC and abundant hemoperitoneum. The technical success rate was 94% (15/16). Day 30 mortality was 19%; the three patients who died had severe hemodynamic instability at admission; one death was due to rebleeding. Liver enzyme levels returned to baseline by day 30. No rebleeding was recorded during the median follow-up of 454 days in the 10 patients who were alive with available data after day 30. Larger prospective studies with the collection of longer-term outcomes are needed to assess our results supporting the safety and effectiveness of cyanoacrylate-lipiodol STAE for rHCC. Randomized trials comparing this mixture to other embolic agents should be performed. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2075-4426 |
Relation: | https://www.mdpi.com/2075-4426/13/11/1581; https://doaj.org/toc/2075-4426 |
DOI: | 10.3390/jpm13111581 |
URL الوصول: | https://doaj.org/article/ca8f1f1870c74155baeaa4c7094d78ac |
رقم الأكسشن: | edsdoj.8f1f1870c74155baeaa4c7094d78ac |
قاعدة البيانات: | Directory of Open Access Journals |
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