دورية أكاديمية
Age Is the Strongest Effector for the Relationship between Estimated Glomerular Filtration Rate and Coronary Artery Calcification in Apparently Healthy Korean Adults
العنوان: | Age Is the Strongest Effector for the Relationship between Estimated Glomerular Filtration Rate and Coronary Artery Calcification in Apparently Healthy Korean Adults |
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المؤلفون: | Hyun Beom Chae, Shin Yeoung Lee, Nam Hee Kim, Ki Joong Han, Tae Hoon Lee, Choel Min Jang, Kyung Mo Yoo, Hae Jung Park, Min Kyung Lee, Won Seon Jeon, Se Eun Park, Heui-Soo Moon, Cheol-Young Park, Won-Young Lee, Ki-Won Oh, Sung-Woo Park, Eun-Jung Rhee |
المصدر: | Endocrinology and Metabolism, Vol 29, Iss 3, Pp 312-319 (2014) |
بيانات النشر: | Korean Endocrine Society, 2014. |
سنة النشر: | 2014 |
المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
مصطلحات موضوعية: | Coronary artery calcification, Glomerular filtration rate, Renal insufficiency, chronic, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
الوصف: | BackgroundChronic kidney disease (CKD) is considered one of the most common risk factors for cardiovascular disease. Coronary artery calcification (CAC) is a potential mechanism that explains the association between renal function and cardiovascular mortality. We aimed to evaluate the association between renal function and CAC in apparently healthy Korean subjects.MethodsA total of 23,617 participants in a health-screening program at Kangbuk Samsung Hospital were included in the study. Estimated glomerular filtration rate (eGFR) was assessed using the Cockcroft-Gault equation. Coronary artery calcium score (CACS) was measured via multidetector computed tomography. Subjects were divided into three groups according to the CKD Staging system with eGFR grade: stage 1, eGFR ≥90 mL/min/1.73 m2; stage 2, eGFR 60 to 89 mL/min/1.73 m2; and stage 3, eGFR 30 to 59 mL/min/1.73 m2.ResultsThe mean age of the participants was 41.4 years and the mean eGFR was 103.6±21.7 mL/min/1.73 m2. Hypertension and diabetes were noted in 43.7% and 5.5% of the participants, respectively. eGFR showed a weakly negative but significant association with CACS in bivariate correlation analysis (r=-0.076, P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English Korean |
تدمد: | 2093-596X 2093-5978 |
Relation: | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-312.pdf; https://doaj.org/toc/2093-596X; https://doaj.org/toc/2093-5978 |
DOI: | 10.3803/EnM.2014.29.3.312 |
URL الوصول: | https://doaj.org/article/8fb4bf68942b4245b8cc4632d3b6da36 |
رقم الأكسشن: | edsdoj.8fb4bf68942b4245b8cc4632d3b6da36 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 2093596X 20935978 |
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DOI: | 10.3803/EnM.2014.29.3.312 |