دورية أكاديمية
A research update on the antitumor effects of active components of Chinese medicine ChanSu
| العنوان: | A research update on the antitumor effects of active components of Chinese medicine ChanSu |
|---|---|
| المؤلفون: | Jinhao Jia, Jie Li, Qiusheng Zheng, Defang Li |
| المصدر: | Frontiers in Oncology, Vol 12 (2022) |
| بيانات النشر: | Frontiers Media S.A., 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | ChanSu, telocinobufagin, bufotalin, bufalin, cinobufotalin, cinobufagin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Clinical data show that the incidence and mortality rates of cancer are rising continuously, and cancer has become an ongoing public health challenge worldwide. Excitingly, the extensive clinical application of traditional Chinese medicine may suggest a new direction to combat cancer, and the therapeutic effects of active ingredients from Chinese herbal medicine on cancer are now being widely studied in the medical community. As a traditional anticancer Chinese medicine, ChanSu has been clinically applied since the 1980s and has achieved excellent antitumor efficacy. Meanwhile, the ChanSu active components (e.g., telocinobufagin, bufotalin, bufalin, cinobufotalin, and cinobufagin) exert great antitumor activity in many cancers, such as breast cancer, colorectal cancer, hepatocellular carcinoma and esophageal squamous cell carcinoma. Many pharmaceutical scientists have investigated the anticancer mechanisms of ChanSu or the ChanSu active components and obtained certain research progress. This article reviews the research progress and antitumor mechanisms of ChanSu active components and proposes that multiple active components of ChanSu may be potential anticancer drugs. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2234-943X |
| Relation: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1014637/full; https://doaj.org/toc/2234-943X |
| DOI: | 10.3389/fonc.2022.1014637 |
| URL الوصول: | https://doaj.org/article/99fd8c25f8854f30857e2cb8227d0466 |
| رقم الأكسشن: | edsdoj.99fd8c25f8854f30857e2cb8227d0466 |
| قاعدة البيانات: | Directory of Open Access Journals |
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