دورية أكاديمية
Rescue of Heart Failure by Mitochondrial Recovery
| العنوان: | Rescue of Heart Failure by Mitochondrial Recovery |
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| المؤلفون: | Jubert Marquez, Sung Ryul Lee, Nari Kim, Jin Han |
| المصدر: | International Neurourology Journal, Vol 20, Iss 1, Pp 5-12 (2016) |
| بيانات النشر: | Korean Continence Society, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | Mitochondria, Heart Failure, Oxidative Stress, Protein Processing, Post-Translational, Mitochondrial Permeability Transition Pore, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Heart failure (HF) is a multifactorial disease brought about by numerous, and oftentimes complex, etiological mechanisms. Although well studied, HF continues to affect millions of people worldwide and current treatments can only prevent further progression of HF. Mitochondria undoubtedly play an important role in the progression of HF, and numerous studies have highlighted mitochondrial components that contribute to HF. This review presents an overview of the role of mitochondrial biogenesis, mitochondrial oxidative stress, and mitochondrial permeability transition pore in HF, discusses ongoing studies that attempt to address the disease through mitochondrial targeting, and provides an insight on how these studies can affect future research on HF treatment. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2093-4777 2093-6931 |
| Relation: | http://www.einj.org/upload/pdf/inj-1632570-285.pdf; https://doaj.org/toc/2093-4777; https://doaj.org/toc/2093-6931 |
| DOI: | 10.5213/inj.1632570.285 |
| URL الوصول: | https://doaj.org/article/9b3f2e64a94b4016ac76bbc62874b4d5 |
| رقم الأكسشن: | edsdoj.9b3f2e64a94b4016ac76bbc62874b4d5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20934777 20936931 |
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| DOI: | 10.5213/inj.1632570.285 |