التفاصيل البيبلوغرافية
العنوان:
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
المؤلفون:
Susan A. Kennedy , Mohamed-Ali Jarboui , Sriganesh Srihari , Cinzia Raso , Kenneth Bryan , Layal Dernayka , Theodosia Charitou , Manuel Bernal-Llinares , Carlos Herrera-Montavez , Aleksandar Krstic , David Matallanas , Max Kotlyar , Igor Jurisica , Jasna Curak , Victoria Wong , Igor Stagljar , Thierry LeBihan , Lisa Imrie , Priyanka Pillai , Miriam A. Lynn , Erik Fasterius , Cristina Al-Khalili Szigyarto , James Breen , Christina Kiel , Luis Serrano , Nora Rauch , Oleksii Rukhlenko , Boris N. Kholodenko , Luis F. Iglesias-Martinez , Colm J. Ryan , Ruth Pilkington , Patrizia Cammareri , Owen Sansom , Steven Shave , Manfred Auer , Nicola Horn , Franziska Klose , Marius Ueffing , Karsten Boldt , David J. Lynn , Walter Kolch
المصدر:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
بيانات النشر:
Nature Portfolio, 2020.
سنة النشر:
2020
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Kras is often mutated in colorectal cancer but how this oncogenic mutation alters signalling pathways globally is undetermined. Here, the authors analyse how this mutation affects protein interaction networks and signal flow showing an extensive re‐wiring of signalling in response to KRas mutation
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
Relation:
https://doaj.org/toc/2041-1723
DOI:
10.1038/s41467-019-14224-9
URL الوصول:
https://doaj.org/article/9d3d9f430d2e481298f1f134583ff8b6
رقم الأكسشن:
edsdoj.9d3d9f430d2e481298f1f134583ff8b6
قاعدة البيانات:
Directory of Open Access Journals
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