Elena G Zemtsova,1 Natalia M Yudintceva,2 Pavel E Morozov,1 Ruslan Z Valiev,1 Vladimir M Smirnov,1 Maxim A Shevtsov2–5 1Saint Petersburg State University, St Petersburg, Russia; 2Institute of Cytology of the Russian Academy of Sciences (RAS), St Petersburg, Russia; 3Pavlov First Saint Petersburg State Medical University, St Petersburg, Russia; 4Polenov Russian Scientific Research Institute of Neurosurgery, Almazov National Medical Research Centre, St Petersburg, Russia; 5Klinikum rechts der Isar, Technical University of Munich, Munich, Germany Background: Titanium (Ti) implants are extensively used in reconstructive surgery and orthopedics. However, the intrinsic inertness of untreated Ti implants usually results in insufficient osseointegration. In order to improve the osteoconductivity properties of the implants, they are coated with hierarchical microtopographic/nanotopographic coatings employing the method of molecular layering of atomic layer deposition (ML-ALD). Results: The analysis of the fabricated nanostructured relief employing scanning electron microscopy, atomic force microscopy, and electron spectroscopy for chemical analysis clearly demonstrated the formation of the nanotopographic (
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