دورية أكاديمية
Genetic Polymorphisms of the Bovine NOV Gene Are Significantly Associated with Carcass Traits in Korean Cattle
| العنوان: | Genetic Polymorphisms of the Bovine NOV Gene Are Significantly Associated with Carcass Traits in Korean Cattle |
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| المؤلفون: | B. S. Kim, S. C. Kim, C. M. Park, S. H. Lee, S. H. Cho, N. K. Kim, G. W. Jang, D. H. Yoon, B. S. Yang, S. K. Hong, H. H. Seong, B. H. Choi |
| المصدر: | Asian-Australasian Journal of Animal Sciences, Vol 26, Iss 6, Pp 780-787 (2013) |
| بيانات النشر: | Asian-Australasian Association of Animal Production Societies, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Animal culture LCC:Animal biochemistry |
| مصطلحات موضوعية: | NOV Gene, Single Nucleotide Polymorphism, Carcass Weight, Back Fat Thickness, Korean Cattle, Animal culture, SF1-1100, Animal biochemistry, QP501-801 |
| الوصف: | The objective of this study was to investigate single nucleotide polymorphisms (SNPs) in the bovine nephroblastoma overexpressed (NOV) gene and to evaluate whether these polymorphisms affect carcass traits in the Korean cattle population. We resequenced to detect SNPs from 24 unrelated individuals and identified 19 SNPs within the full 8.4-kb gene, including the 1.5-kb promoter region. Of these 19 SNPs, four were selected for genotyping based on linkage disequilibrium (LD). We genotyped 429 steers to assess the associations of these four SNPs with carcass traits. Statistical analysis revealed that g.7801T>C and g.8379A>C polymorphisms in the NOV gene were associated with carcass weight (p = 0.012 and 0.008, respectively), and the g.2005A>G polymorphism was associated with the back fat thickness (BF) trait (p = 0.0001). One haplotype of the four SNPs (GGTA) was significantly associated with BF (p = 0.0005). Our findings suggest that polymorphisms in the NOV gene may be among the important genetic factors affecting carcass yield in beef cattle. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1011-2367 1976-5517 |
| Relation: | http://www.ajas.info/upload/pdf/ajas-26-6-780-4.pdf; https://doaj.org/toc/1011-2367; https://doaj.org/toc/1976-5517 |
| DOI: | 10.5713/ajas.2012.12514 |
| URL الوصول: | https://doaj.org/article/c9efbf73d5eb418fbdcd129217543caa |
| رقم الأكسشن: | edsdoj.9efbf73d5eb418fbdcd129217543caa |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10112367 19765517 |
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| DOI: | 10.5713/ajas.2012.12514 |