دورية أكاديمية
Molecular characterization of plasma virome of hepatocellular carcinoma (HCC) patients
| العنوان: | Molecular characterization of plasma virome of hepatocellular carcinoma (HCC) patients |
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| المؤلفون: | Niamat Ullah Khan, Asma Sadiq, Jadoon Khan, Nosheen Basharat, Zulfiqar Ul Hassan, Ijaz Ali, Tawaf Ali Shah, Mohammed Bourhia, Yousef A. Bin Jardan, Gezahign Fentahun Wondmie |
| المصدر: | AMB Express, Vol 14, Iss 1, Pp 1-11 (2024) |
| بيانات النشر: | SpringerOpen, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Biotechnology LCC:Microbiology |
| مصطلحات موضوعية: | Metagenomics, Anelloviruses, Viral etiologies, Hepatocellular carcinoma, Pathogenesis, Biotechnology, TP248.13-248.65, Microbiology, QR1-502 |
| الوصف: | Abstract Hepatocellular carcinoma (HCC) stands as the most common cancer type, arising from various causes, and responsible for a substantial number of cancer-related fatalities. Recent advancements in viral metagenomics have empowered scientists to delve into the intricate diversity of the virosphere, viral evolution, interactions between viruses and their hosts, and the identification of viral causes behind disease outbreaks, the development of specific symptoms, and their potential role in altering the host’s physiology. The present study had the objective of “Molecular Characterization of HBV, HCV, anelloviruses, CMV, SENV-D, SENV-H, HEV, and HPV viruses among individuals suffering from HCC.” A total of 381 HCC patients contributed 10 cc of blood each for this study. The research encompassed the assessment of tumor markers, followed by molecular characterization of HBV, HCV, Anelloviruses (TTV, TTMV, and TTMDV), SENV-H and SENV-D viruses, HEV, CMV, and HPV, as well as histopathological examinations. The outcomes of this study revealed that majority of the HCC patients 72.4% (276/381) were male as compared to females. HCV infection, at 76.4% (291 out of 381), exhibited a significant association (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2191-0855 |
| Relation: | https://doaj.org/toc/2191-0855 |
| DOI: | 10.1186/s13568-024-01696-2 |
| URL الوصول: | https://doaj.org/article/9f99434ccae54ebb89611cf14d15e27b |
| رقم الأكسشن: | edsdoj.9f99434ccae54ebb89611cf14d15e27b |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 21910855 |
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| DOI: | 10.1186/s13568-024-01696-2 |