دورية أكاديمية
Determination of the minimum infective dose of viral hemorrhagic septicemia virus (VHSV) in juvenile olive flounder, Paralichthys olivaceus using an immersion challenge model
| العنوان: | Determination of the minimum infective dose of viral hemorrhagic septicemia virus (VHSV) in juvenile olive flounder, Paralichthys olivaceus using an immersion challenge model |
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| المؤلفون: | Su-Young Yoon, Yo-Seb Jang, Soo-Jin Kim, Rahul Krishnan, Myung-Joo Oh |
| المصدر: | Virus Research, Vol 340, Iss , Pp 199305- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Microbiology LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Minimum infective dose, Viral hemorrhagic septicemia virus, Olive flounder, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Viral hemorrhagic septicemia virus (VHSV) affects over 80 fish species, leading to viral hemorrhagic septicemia (VHS). Horizontal VHSV transmission is widely studied, with researchers utilizing various doses to establish infection models. Infected hosts shed the virus into the environment, elevating the risk of transmission to naïve fish within the same system. This study aimed to ascertain the minimum infective dose of VHSV in olive flounder (Paralichthys olivaceus). In olive flounder, the detection of VHSV within the kidney exhibited the highest infection rate on the third day among days 1, 3 and 5. Doses of 103.0 to 104.7 TCID50/ml were administered to juvenile olive flounder across three farms. Results showed resistance to infection below 103.4 TCID50/ml at 15 °C. While infection frequency varied by concentration, higher concentrations correlated with more infections. Nonetheless, viral copy numbers did not differ significantly among infected fish at varying concentrations. This study underscores the need for early VHSV management and contributes essential data for pathogenicity assessment and foundational knowledge. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1872-7492 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S0168170223002678; https://doaj.org/toc/1872-7492 |
| DOI: | 10.1016/j.virusres.2023.199305 |
| URL الوصول: | https://doaj.org/article/ab1e9f16de0840ee84bfde9e52b7ef41 |
| رقم الأكسشن: | edsdoj.b1e9f16de0840ee84bfde9e52b7ef41 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18727492 |
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| DOI: | 10.1016/j.virusres.2023.199305 |