ObjectiveTo explore the predictive value of predialysis plasma osmolality for frequent intradialytic hypotension (IDH) in elders on maintenance hemodialysis (MHD).MethodsAccording to whether or not there was frequent IDH, 301 MHD elders were assigned into two groups of control (n=257) and frequent IDH (n=44). General profiles, laboratory parameters and cardiac B-ultrasound examinations were recorded. The risk factors for frequent IDH were identified by multivariate Logistic regression. Receiver operating characteristic (ROC) curve was plotted for exploring the predictive efficacy of predialysis plasma osmolality for frequent IDH.ResultsAs compared with control group, ultrafiltration rate, parathyroid hormone (PTH) and predialysis plasma osmolality spiked obviously while hemoglobin, serum albumin (Alb), left ventricular ejection fraction (LVEF) and Kt/V declined markedly in frequent IDH group (all P