دورية أكاديمية
Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days
| العنوان: | Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days |
|---|---|
| المؤلفون: | Yirui Shao, Xia Xiong, Kexing Wang, Pi Cheng, Lijun Zou, Jian Zhou, Ming Qi, Yulong Yin |
| المصدر: | Animal Nutrition, Vol 11, Iss , Pp 102-111 (2022) |
| بيانات النشر: | KeAi Communications Co., Ltd., 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Animal culture |
| مصطلحات موضوعية: | Early-weaned piglet, Weaning stress, Crypt cell, Lipidomics, Inflammation, Animal culture, SF1-1100 |
| الوصف: | Reportedly, proteins involved in lipid metabolism change significantly in the jejunal crypt cells of early-weaned piglets, but the exact lipid profile change remains uncertain. In the present study, 32 piglets weaned at 21 d of age were randomly divided into 4 groups with 8 replicates. The jejunal crypt cells of a group of piglets on the post-weaning day (PWD) 1, 3, 7, and 14 were isolated per time point. Crypt cell lipid profiles were analyzed using ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry. This study showed that piglets suffered the greatest weaning stress on PWD 3 in terms of the lowest relative weight of the small intestine, the highest relative weight of the spleen, and the highest levels of malondialdehyde, cholesterol, and low-density lipoprotein cholesterol. The lipid profile of jejunal crypt cells including carnitine, sulfatide, sphingomyelin, hexosylceramide, and ceramide greatly changed after weaning, especially between PWD 3 and 14 (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2405-6545 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2405654522000865; https://doaj.org/toc/2405-6545 |
| DOI: | 10.1016/j.aninu.2022.07.001 |
| URL الوصول: | https://doaj.org/article/b3a84b401da446f6a4e76d3d51f3d09b |
| رقم الأكسشن: | edsdoj.b3a84b401da446f6a4e76d3d51f3d09b |
| قاعدة البيانات: | Directory of Open Access Journals |
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