دورية أكاديمية
Targeting the macrophage immunocheckpoint: a novel insight into solid tumor immunotherapy
| العنوان: | Targeting the macrophage immunocheckpoint: a novel insight into solid tumor immunotherapy |
|---|---|
| المؤلفون: | Bei Zhou, Yan Yang, Yan Kang, Jingjing Hou, Yun Yang |
| المصدر: | Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-11 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Cytology |
| مصطلحات موضوعية: | Macrophage, Solid tumor, Immunotherapy, Immune factors, Medicine, Cytology, QH573-671 |
| الوصف: | Abstract Tumor immunotherapy, which targets immune checkpoints, presents a promising strategy for the treatment of various cancer types. However, current clinical data indicate challenges in its application to solid tumors. Recent studies have revealed a significant correlation between the degree of immune response in immunotherapy and the tumor microenvironment, particularly with regard to tumor-infiltrating immune cells. Among these immune cells, macrophages, a critical component, are playing an increasingly vital role in tumor immunotherapy. This review focuses on elucidating the role of macrophages within solid tumors and provides an overview of the progress in immunotherapy approaches centered around modulating macrophage responses through various immune factors. Video Abstract |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1478-811X |
| Relation: | https://doaj.org/toc/1478-811X |
| DOI: | 10.1186/s12964-023-01384-x |
| URL الوصول: | https://doaj.org/article/b4b7e04d7d3c4c928cfbde4bac66a6ff |
| رقم الأكسشن: | edsdoj.b4b7e04d7d3c4c928cfbde4bac66a6ff |
| قاعدة البيانات: | Directory of Open Access Journals |
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