دورية أكاديمية
Immunohistological localisation of growth factors in stroma and interstitial gland tissue of goat (Capra hircus) ovary
العنوان: | Immunohistological localisation of growth factors in stroma and interstitial gland tissue of goat (Capra hircus) ovary |
---|---|
المؤلفون: | S. Saini, R. A. Bhat |
المصدر: | Bulgarian Journal of Veterinary Medicine, Vol 24, Iss 4, Pp 478-486 (2021) |
بيانات النشر: | Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Veterinary medicine |
مصطلحات موضوعية: | goat, ovary, pdgf, stroma, tgf-α, tgf-β, Veterinary medicine, SF600-1100 |
الوصف: | The growth factors platelet derived growth factor (PDGF), transforming growth factor alpha (TGF-α) and transforming growth factor beta (TGF-β) have been demonstrated to stimulate the in vitro proliferation of theca and granulosa cells in different animals. The present study was conducted to localise the growth factors PDGF, TGF-α and TGF-β in different types of interstitial cells and stromal cells of normal cycling goat ovaries. Tissue fixed in formalin was processed through a graded series of alcohols and embedded in paraffin wax. The sections were immunohistochemically stained with antibodies against PDGF, TGF-α and TGF-β. The binding affinity of interstitial cells and stromal cells were observed and photographed. The staining pattern of PDGF, TGF-α and TGF-β was mild to strong in stromal cells. The primary and secondary interstitial cells exhibited varied staining patterns for all studied growth factors. These findings in goat suggests that PDGF, TGF-α, TGF-β were potentially an important autocrine regulator of different cell functions and possibly a paracrine regulator of ovarian cell function at various development stages. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1311-1477 1313-3543 |
Relation: | https://doaj.org/toc/1311-1477; https://doaj.org/toc/1313-3543 |
DOI: | 10.15547/bjvm.2316 |
URL الوصول: | https://doaj.org/article/b57da451115d42a38108344813814ca9 |
رقم الأكسشن: | edsdoj.b57da451115d42a38108344813814ca9 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 13111477 13133543 |
---|---|
DOI: | 10.15547/bjvm.2316 |