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Association between serum bilirubin levels and progression of albuminuria in Taiwanese with type 2 diabetes mellitus

التفاصيل البيبلوغرافية
العنوان: Association between serum bilirubin levels and progression of albuminuria in Taiwanese with type 2 diabetes mellitus
المؤلفون: Wai Kin Chan, Sung-Sheng Tsai, Yan-Rong Li, Wei-Yu Chou, Hsiao-Lien Chen, Szu-Tah Chen
المصدر: Biomedical Journal, Vol 44, Iss 2, Pp 201-208 (2021)
بيانات النشر: Elsevier, 2021.
سنة النشر: 2021
المجموعة: LCC:Medicine (General)
LCC:Biology (General)
مصطلحات موضوعية: Albuminuria, Bilirubin, Chronic kidney diseases, Diabetic nephropathy, Medicine (General), R5-920, Biology (General), QH301-705.5
الوصف: Background: To investigate the association between serum bilirubin (BIL) levels and the progression of albuminuria in type 2 diabetic Taiwanese. Methods: Longitudinal data from January 2001 to June 2015 were retrospectively reviewed from Chang Gung Memorial Hospital in Taiwan. A total of 2877 type 2 diabetic patients with normal total BIL levels were divided into 4 groups according to BIL, with the highest BIL in the fourth group. The urinary albumin/creatinine ratio (UACR) trend and progression, as well as other laboratory measurements, were evaluated among the four groups. The cumulative incidence and Cox proportional hazard model analysis were performed to examine the relationship between BIL and the risk of albuminuria progression (AUPr). Results: The mean duration of follow-up was 1.5 years (±1.37 years). The mean patient age, glycosylated hemoglobin level, and duration of diabetes were 62.52 years, 7.9%, and 3.94 years, respectively. A significant correlation was observed between BIL and both the UACR at baseline (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2319-4170
Relation: http://www.sciencedirect.com/science/article/pii/S2319417019305268; https://doaj.org/toc/2319-4170
DOI: 10.1016/j.bj.2019.12.004
URL الوصول: https://doaj.org/article/b7ab1fb9496e4d61bb051a29240ca06d
رقم الأكسشن: edsdoj.b7ab1fb9496e4d61bb051a29240ca06d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23194170
DOI:10.1016/j.bj.2019.12.004