دورية أكاديمية
Prevalence and characteristics of multidrug-resistant Proteus mirabilis from broiler farms in Shandong Province, China
| العنوان: | Prevalence and characteristics of multidrug-resistant Proteus mirabilis from broiler farms in Shandong Province, China |
|---|---|
| المؤلفون: | Zixuan Li, Chong Peng, Gerui Zhang, Yuanyu Shen, Yuxuan Zhang, Cong Liu, Mengda Liu, Fangkun Wang |
| المصدر: | Poultry Science, Vol 101, Iss 4, Pp 101710- (2022) |
| بيانات النشر: | Elsevier, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Animal culture |
| مصطلحات موضوعية: | P. mirabilis, multidrug-resistant, blaNDM-1, virulence gene, Animal culture, SF1-1100 |
| الوصف: | ABSTRACT: Animal-derived Proteus mirabilis (P. mirabilis) is an important food-borne zoonotic bacillus and widely exists in the broiler-breeding industry. The present study was designed to explore the P. mirabilis prevalence and antimicrobial resistance characteristics in 6 conventional broiler-fattening farms in Shandong Province, China. The overall isolation rate of P. mirabilis was 7.07% (50/707). Antimicrobial resistance was very common in the P. mirabilis isolated from these farms and varied for different antibacterial drugs, with chloramphenicol, ciprofloxacin, and trimethoprim-sulfamethoxazole having the highest resistance rate (98%) and aztreonam the lowest (0%). Multidrug resistance was as high as 100%. The majority of the MDR isolates were resistant to between 9 and 12 of the antibiotics, with these accounting for 76% (38/50) of multidrug resistant strains. These P. mirabilis isolates carried 24 drug-resistance genes in 6 types, with stcM having the highest rate (96%) and cmlA, blaTEM, and qnrC the lowest (2%). Superdrug resistance gene blaNDM-1 was found in 10% (5/50) of isolates from poultry farms in Shandong. All the P. mirabilis isolates carried at least 6 virulence genes, with 100% detection rates of the ireA and hpmA genes. Our study revealed that the P. mirabilis strains isolated in the Shandong area all showed the MDR phenotype and the poultry-derived carbapenem-resistant MDR P. mirabilis strains may pose a potential risk to humans. Surveillance findings presented herein will be conducive to our understanding of the prevalence and characteristics of carbapenem-resistant P. mirabilis strains in Shandong, China. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0032-5791 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S0032579122000153; https://doaj.org/toc/0032-5791 |
| DOI: | 10.1016/j.psj.2022.101710 |
| URL الوصول: | https://doaj.org/article/abcc9663481442208531a7b0132e9d1f |
| رقم الأكسشن: | edsdoj.bcc9663481442208531a7b0132e9d1f |
| قاعدة البيانات: | Directory of Open Access Journals |
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