دورية أكاديمية
Metabolic disorders and blood fatty acids status in hospitalized very old patients: part I of the Alpha-linolenage study⋆⋆⋆
| العنوان: | Metabolic disorders and blood fatty acids status in hospitalized very old patients: part I of the Alpha-linolenage study⋆⋆⋆ |
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| المؤلفون: | Henry Olivier, Combe Nicole, Vaysse Carole, Lopez Carlos, Driss Fathi, Fonseca Isabelle, Simon Noëmie, Le Guillou Céline, Masselin-Silvin Sylvie, David Jean-Philippe, Mendy François |
| المصدر: | Oilseeds and fats, crops and lipids, Vol 22, Iss 3, p D305 (2015) |
| بيانات النشر: | EDP Sciences, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Oils, fats, and waxes |
| مصطلحات موضوعية: | Alpha-linolenage study, fatty acids, elderly, ALA, PUFA, rapeseed oil, Oils, fats, and waxes, TP670-699 |
| الوصف: | Background: previous studies showed that hospitalized elderly women had low Polyunsaturated fatty acids (PUFA) intake and concomitantly showed biochemical indices of essential fatty acid (EFA) insufficiency. Objectives: the Alpha-Linolenage study aimed to improve health parameters of hospitalized very elderly patients, aged 85 years. The objective of the Part I of the Alpha-linolenage study was to assess blood fatty acid status and parameters of metabolic disorders of these patients at the baseline. Design: from 2009 to 2011, 188 patients entering the geriatric department of Emile Roux Hospitals, Île-de-France region, France, were included. Data on the lipid status were obtained through analysis of fatty acid compositions of plasma cholesterol esters and erythrocyte phospholipids. Results: because of our inclusion criteria, there was a high prevalence of CV disease, affecting 74% of our participants. Patients ingested an average of 1586 kcal per day. Fat accounted for 49.2 g/d. Both LA and ALA intakes were not reached, i.e. on average 5 g/d of LA vs. 8–10 g and 1.2 g/d of ALA vs. 2–2.5 g recommended, respectively. The LA and ALA blood status reflected this situation; their contents were lower than those waited under sufficient EFA diet. Conclusion: in very elderly patients a status of chronic disease may generate CV or mortality risk factors. A low fat intake, with both insufficient LA and ALA intakes might favor the harmful role played by de novo lipogenesis, Indeed, a cornerstone of dietary guidelines, i.e. restriction of fat and saturated fat, may be related to risk of disease. The second part of the alpha-linolenage study will aim to improve markers of the metabolic disorders by providing sufficiently lipids. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English French |
| تدمد: | 2272-6977 2257-6614 |
| Relation: | https://doaj.org/toc/2272-6977; https://doaj.org/toc/2257-6614 |
| DOI: | 10.1051/ocl/2015018 |
| URL الوصول: | https://doaj.org/article/f070dd9710784b149f6d84c69f913b41 |
| رقم الأكسشن: | edsdoj.f070dd9710784b149f6d84c69f913b41 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22726977 22576614 |
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| DOI: | 10.1051/ocl/2015018 |