دورية أكاديمية
Lung (extracorporeal CO2 removal) and renal (continuous renal replacement therapy) support: the role of ultraprotective strategy in Covid 19 and non-Covid 19 ARDS. A case-control study
العنوان: | Lung (extracorporeal CO2 removal) and renal (continuous renal replacement therapy) support: the role of ultraprotective strategy in Covid 19 and non-Covid 19 ARDS. A case-control study |
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المؤلفون: | Daniela Pasero, Laura Pistidda, Davide Piredda, Corrado Liperi, Andrea Cossu, Raffaella Esposito, Angela Muroni, Cristiano Mereu, Carlino Rum, Gian Pietro Branca, Franco Mulas, Mariangela Puci, Giovanni Sotgiu, Pierpaolo Terragni |
المصدر: | Journal of Anesthesia, Analgesia and Critical Care, Vol 4, Iss 1, Pp 1-16 (2024) |
بيانات النشر: | BMC, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Anesthesiology LCC:Medical emergencies. Critical care. Intensive care. First aid |
مصطلحات موضوعية: | ARDS, Lung-protective ventilatory strategy, Low-Flow CO2 removal, AKI, CRRT, COVID-19, Anesthesiology, RD78.3-87.3, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9 |
الوصف: | Abstract Background Preliminary studies suggest that moderate ARDS and acute renal failure might benefit from extracorporeal CO2 removal (ECCO2R) coupled with CRRT. However, evidence is limited and potential for this coupled treatment may need to be explored. The aim of the present study was to evaluate whether a protective driving pressure was obtained applying low-flow ECCO2-R plus CRRT in patients affected by moderate ARDS with COVID-19 compared to an historical group without COVID-19. Methods A case-control study has been conducted comparing a group of consecutive moderate ARDS patients presenting AKI and affected by COVID-19, who needed low-flow ECCO2-R plus CRRT to achieve an ultra-protective ventilatory strategy, with historical group without COVID-19 that matched for clinical presentation and underwent the same ultra-protective treatment. VT was set at 6 mL/kg predicted body weight then ECCO2R was assessed to facilitate ultra-protective low VT ventilation to preserve safe Pplat and low driving pressure. Results ECCO2R+CRRT reduced the driving pressure from 17 (14-18) to 11.5 (10-15) cmH2O (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2731-3786 |
Relation: | https://doaj.org/toc/2731-3786 |
DOI: | 10.1186/s44158-024-00164-4 |
URL الوصول: | https://doaj.org/article/f0fa2f8dd4984146be4ea8e7fc078d06 |
رقم الأكسشن: | edsdoj.f0fa2f8dd4984146be4ea8e7fc078d06 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 27313786 |
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DOI: | 10.1186/s44158-024-00164-4 |