دورية أكاديمية
Cytomegalovirus Endotheliitis After Penetrating Keratoplasty
| العنوان: | Cytomegalovirus Endotheliitis After Penetrating Keratoplasty |
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| المؤلفون: | Tuna Çelik Büyüktepe, Nilüfer Yalçındağ |
| المصدر: | Türk Oftalmoloji Dergisi, Vol 50, Iss 5, Pp 304-307 (2020) |
| بيانات النشر: | Galenos Yayinevi, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medicine LCC:Ophthalmology |
| مصطلحات موضوعية: | penetrating keratoplasty, cytomegalovirus, viral endotheliitis, graft rejection, Medicine, Ophthalmology, RE1-994 |
| الوصف: | Cytomegalovirus (CMV)-related corneal endotheliitis is an inflammation of the corneal endothelium caused by CMV. It may occur de novo or after ocular surgery in otherwise healthy individuals. In patients who have undergone keratoplasty, the differential diagnosis of viral endotheliitis and immune-related graft rejection is challenging due to the similar clinical findings. Here we report a patient who underwent penetrating keratoplasty and was using local and systemic immunosuppressive agents due to previous history of graft rejection. At postoperative year 4, ophthalmologic examination revealed localized corneal edema, coin-shaped keratic precipitates, and increased intraocular pressure, consistent with viral endotheliitis. Polymerase chain reaction revealed CMV-DNA amplification in the aqueous humor sample. Valganciclovir treatment was started and the symptoms improved in 2 months. It should be kept in mind that local or systemic immunosuppressants used after keratoplasty may trigger CMV reactivation. Anti-CMV treatment should be initiated immediately in patients with coin-shaped keratic precipitates. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Turkish |
| تدمد: | 1300-0659 2147-2661 |
| Relation: | http://www.oftalmoloji.org/archives/archive-detail/article-preview/cytomegalovirus-endotheliitis-after-penetrating-ke/41738; https://doaj.org/toc/1300-0659; https://doaj.org/toc/2147-2661 |
| DOI: | 10.4274/tjo.galenos.2020.47568 |
| URL الوصول: | https://doaj.org/article/f3751da9f0f04e21a858d3138769da1b |
| رقم الأكسشن: | edsdoj.f3751da9f0f04e21a858d3138769da1b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13000659 21472661 |
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| DOI: | 10.4274/tjo.galenos.2020.47568 |