دورية أكاديمية
The Effect of Continuous Ventilation on Thiol-Disulphide Homeostasis and Albumin-Adjusted Ischemia-Modified Albumin During Cardiopulmonary Bypass
| العنوان: | The Effect of Continuous Ventilation on Thiol-Disulphide Homeostasis and Albumin-Adjusted Ischemia-Modified Albumin During Cardiopulmonary Bypass |
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| المؤلفون: | Seyda Efsun Ozgunay, Kadir Kaan Ozsin, Yasemin Ustundag, Derya Karasu, Buket Ozyaprak, Burak Balcı, Ozcan Erel, Senol Yavuz |
| المصدر: | Brazilian Journal of Cardiovascular Surgery, Vol 34, Iss 4, Pp 436-443 |
| بيانات النشر: | Sociedade Brasileira de Cirurgia Cardiovascular. |
| المجموعة: | LCC:Surgery LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Coronary Artery Bypass, Mechanical Ventilation, Ischemia-Modified Albumin, Disulfides, Sulfhydryl Compounds, Biomarkers, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Abstract Objective: To investigate the effect of continuous lung ventilation with low tidal volume on oxidation parameters, such as thiol/disulphide homeostasis and albumin-adjusted ischemia-modified albumin (AAIMA), during cardiopulmonary bypass (CBP) in coronary artery bypass grafting (CABG). Methods: Seventy-four patients who underwent elective CABG with CPB were included in the study. Blood samples were taken in the preoperative period, 10 minutes after CPB, and six and 24 hours postoperatively. Patients were assigned to the continuous ventilation group (Group 1, n=37) and the non-ventilated group (Group 2, n=37). The clinical characteristics, thiol/disulphide homeostasis, ischemia-modified albumin (IMA), and AAIMA levels of the patients were compared. Results: A significant difference was found between the groups regarding native thiol, total thiol, and IMA levels at the postoperative 24th hour (P=0.030, P=0.031, and P=0.004, respectively). There was no difference between the groups in terms of AAIMA. AAIMA levels returned to preoperative levels in Groups 1 and 2, at the 6th and 24th postoperative hours, respectively. Length of hospital stay was significantly shorter in Group 1 (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-9741 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000400011&lng=en&tlng=en; https://doaj.org/toc/1678-9741 |
| DOI: | 10.21470/1678-9741-2018-0398 |
| URL الوصول: | https://doaj.org/article/f48f3d0056504ea8bf1fcb14839f89aa |
| رقم الأكسشن: | edsdoj.f48f3d0056504ea8bf1fcb14839f89aa |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 16789741 |
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| DOI: | 10.21470/1678-9741-2018-0398 |