دورية أكاديمية
Critical Illness Polyneuropathy and Myopathy and Clinical Detection of the Recovery of Consciousness in Severe Acquired Brain Injury Patients with Disorders of Consciousness after Rehabilitation
| العنوان: | Critical Illness Polyneuropathy and Myopathy and Clinical Detection of the Recovery of Consciousness in Severe Acquired Brain Injury Patients with Disorders of Consciousness after Rehabilitation |
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| المؤلفون: | Bahia Hakiki, Francesca Cecchi, Silvia Pancani, Anna Maria Romoli, Francesca Draghi, Maenia Scarpino, Raisa Sterpu, Andrea Mannini, Claudio Macchi, Antonello Grippo |
| المصدر: | Diagnostics, Vol 12, Iss 2, p 516 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | severe acquired brain injury, disorders of consciousness, critical illness polyneuropathy and myopathy, Coma Recovery Scale-Revised, neurophysiology, rehabilitation, Medicine (General), R5-920 |
| الوصف: | Background: Disorders of consciousness (DoCs) include unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS). Critical illness polyneuropathy and myopathy (CIPNM) is frequent in severe acquired brain injuries and impacts functional outcomes at discharge from the intensive rehabilitation unit (IRU). We investigated the prevalence of CIPNM in DoCs and its relationship with the consciousness assessment. Methods: Patients with DoCs were retrospectively selected from the database including patients admitted to the IRU of the IRCCS Don Gnocchi Foundation, Florence, from August 2012 to May 2020. Electroneurography/electromyography was performed at admission. Consciousness was assessed using the Coma Recovery Scale-Revised (CRS-R) at admission and discharge. Patients transitioning from a lower consciousness state to a higher one were classified as improved responsiveness (IR). Results: A total of 177 patients were included (UWS: 81 (45.8%); MCS: 96 (54.2%); 78 (44.1%) women; 67 years (IQR: 20). At admission, 108 (61.0%) patients had CIPNM. At discharge, 117 (66.1%) patients presented an IR. In the multivariate analysis, CRS-R at admission (p = 0.006; OR: 1.462) and CIPNM (p = 0.039; OR: −1.252) remained significantly associated with IR only for the UWS patients. Conclusions: CIPNM is frequent in DoCs and needs to be considered during the clinical consciousness assessment, especially in patients with UWS. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 12020516 2075-4418 |
| Relation: | https://www.mdpi.com/2075-4418/12/2/516; https://doaj.org/toc/2075-4418 |
| DOI: | 10.3390/diagnostics12020516 |
| URL الوصول: | https://doaj.org/article/af6a7f70922b4808ad64e054972f2914 |
| رقم الأكسشن: | edsdoj.f6a7f70922b4808ad64e054972f2914 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 12020516 20754418 |
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| DOI: | 10.3390/diagnostics12020516 |