دورية أكاديمية
Successful use of rivaroxaban achieving therapeutic anti-factor xa levels in a morbidly obese patient with acute intermediate-high risk pulmonary embolism
| العنوان: | Successful use of rivaroxaban achieving therapeutic anti-factor xa levels in a morbidly obese patient with acute intermediate-high risk pulmonary embolism |
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| المؤلفون: | Kingsley Dah, Mateo Porres-Aguilar, Alan De la Rosa, Swathi Prakash |
| المصدر: | Jornal Vascular Brasileiro, Vol 22 (2023) |
| بيانات النشر: | Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV), 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Surgery LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | direct oral anticoagulants, rivaroxaban, venous thromboembolism, morbid obesity, acute pulmonary embolism, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Abstract Direct oral anticoagulants (DOACs) have become the standard of care for acute and long-term therapy for venous thromboembolism (VTE) due to their efficacy and safety profiles. The 2021 International Society on Thrombosis and Haemostasis guidelines recommend using standard DOAC dosages in patients with BMI >40 kg/m2 or weight >120 kg. Use of DOACs remains uncertain in morbidly obese patients with VTE, including acute PE. A morbidly obese woman in her 30s who presented with acute worsening of dyspnea was diagnosed with acute intermediate-high risk acute pulmonary embolism and concomitant proximal deep vein thrombosis, constituting a clinically challenging scenario for treating her with rivaroxaban. Standard doses of rivaroxaban for acute and extended phase treatment of venous thromboembolism in individuals with morbid obesity at BMI>70 kg/m2 may be effective, and safe. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 1677-7301 1677-5449 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492023000100502&tlng=en; https://doaj.org/toc/1677-7301 |
| DOI: | 10.1590/1677-5449.202300562 |
| URL الوصول: | https://doaj.org/article/fada7004579647cca5b63c4ab1f247c5 |
| رقم الأكسشن: | edsdoj.fada7004579647cca5b63c4ab1f247c5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16777301 16775449 |
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| DOI: | 10.1590/1677-5449.202300562 |