دورية أكاديمية
Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease
العنوان: | Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease |
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المؤلفون: | Juan P. Zuniga-Hertz, Ramamurthy Chitteti, Joe Dispenza, Raphael Cuomo, Jacqueline A. Bonds, Elena L. Kopp, Sierra Simpson, Jonathan Okerblom, Svetlana Maurya, Brinda K. Rana, Atsushi Miyonahara, Ingrid R. Niesman, Jacqueline Maree, Gianna Belza, Hillari D. Hamilton, Carla Stanton, David J. Gonzalez, Michelle A. Poirier, Tobias Moeller-Bertram, Hemal H. Patel |
المصدر: | Brain, Behavior, & Immunity - Health, Vol 32, Iss , Pp 100675- (2023) |
بيانات النشر: | Elsevier, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
مصطلحات موضوعية: | Meditation, Immunity, Adoptive blood transfer, serpin, SARS-CoV-2, Pseudovirus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
الوصف: | The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide. Management of the pandemic has relied mainly on SARS-CoV-2 vaccines, while alternative approaches such as meditation, shown to improve immunity, have been largely unexplored. Here, we probe the relationship between meditation and COVID-19 disease and directly test the impact of meditation on the induction of a blood environment that modulates viral infection. We found a significant inverse correlation between length of meditation practice and SARS-CoV-2 infection as well as accelerated resolution of symptomology of those infected. A meditation “dosing” effect was also observed. In cultured human lung cells, blood from experienced meditators induced factors that prevented entry of pseudotyped viruses for SARS-CoV-2 spike protein of both the wild-type Wuhan-1 virus and the Delta variant. We identified and validated SERPINA5, a serine protease inhibitor, as one possible protein factor in the blood of meditators that is necessary and sufficient for limiting pseudovirus entry into cells. In summary, we conclude that meditation can enhance resiliency to viral infection and may serve as a possible adjuvant therapy in the management of the COVID-19 pandemic. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2666-3546 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2666354623000893; https://doaj.org/toc/2666-3546 |
DOI: | 10.1016/j.bbih.2023.100675 |
URL الوصول: | https://doaj.org/article/dfbdeaceac4345899555a7cf3860a8bb |
رقم الأكسشن: | edsdoj.fbdeaceac4345899555a7cf3860a8bb |
قاعدة البيانات: | Directory of Open Access Journals |
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