دورية أكاديمية
Efficacy and Systemic Safety of Epidermal Growth Factor plus Silver Sulfadiazine Cream for the Treatment of Partial Thickness Burn Wounds
| العنوان: | Efficacy and Systemic Safety of Epidermal Growth Factor plus Silver Sulfadiazine Cream for the Treatment of Partial Thickness Burn Wounds |
|---|---|
| المؤلفون: | Nantaporn Namviriyachote, Pornprom Muangman, Pornanong Aramwit |
| المصدر: | Journal of Health Science and Medical Research (JHSMR), Vol 30, Iss 4, Pp 209-220 (2012) |
| بيانات النشر: | Prince of Songkla University, 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | burn wound, epidermal growth factor, safety, silver sulfadiazine, Medicine |
| الوصف: | Objective: This clinical study was undertaken to investigate the efficacy and safety of topical Epidermal Growth Factor (EGF) plus silver sulfadiazine cream for the treatment of partial thickness burn wounds. Material and Methods: This investigation was a prospective clinical study in patients with partial thickness burn wounds. Patients eligible for this study must have burn area higher than 20% of total body surface area and be aged between 18 and 60 years. Total of 9 patients was recruited into this study and all patients were treated with EGF plus silver sulfadiazine cream once daily for consecutively 4 weeks. Pain score was evaluated using a visual analog scale and blood serum was used to evaluate liver and kidney function on the day of enrollment and on the 7th, 14th, 21st and 28th day of treatment. Results: Average pain score was the highest at the first time of treatment and then significantly declined after that. Liver and kidney functions were almost in normal range except aspartate aminotransferase (AST) and alanine transaminase (ALT), which were a little over the upper limit at initial of treatment then subsided to normal in the second week. There was no abnormality at the wound site throughout the study. Conclusion: It is concluded that EGF plus silver sulfadiazine cream is safe for the treatment of partial thickness burn wounds. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2586-9981 2630-0559 |
| Relation: | https://www.jhsmr.org/index.php/jhsmr/article/view/291; https://doaj.org/toc/2586-9981; https://doaj.org/toc/2630-0559 |
| URL الوصول: | https://doaj.org/article/afc5c517cbac40b99d59cbd206ef5348 |
| رقم الأكسشن: | edsdoj.fc5c517cbac40b99d59cbd206ef5348 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 25869981 26300559 |
|---|