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Optical coherence tomography biomarkers for myopic choroidal neovascularization treated with anti‐vascular endothelial growth factor

التفاصيل البيبلوغرافية
العنوان: Optical coherence tomography biomarkers for myopic choroidal neovascularization treated with anti‐vascular endothelial growth factor
المؤلفون: Daniel Yu Lee, Po‐Ying Wu, Shwu‐Jiuan Sheu
المصدر: Kaohsiung Journal of Medical Sciences, Vol 39, Iss 6, Pp 637-643 (2023)
بيانات النشر: Wiley, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: choroidal neovascularization, myopia, optical coherence tomography biomarker, vascular endothelial growth factor, Medicine (General), R5-920
الوصف: Abstract In recent years, optical coherence tomography (OCT) biomarkers for specific retinal diseases have been found to be associated with treatment outcome and disease recurrence. The main purposes of this study were to identify OCT biomarkers for myopic choroidal neovascularization (mCNV) treated with intravitreal injection of anti‐vascular endothelial growth factor (anti‐VEGF). OCT features in 43 eyes of 39 patients with mCNV treated with anti‐VEGF with at least 1 year of follow‐up were retrospectively analyzed. Eyes with subretinal hyperreflective material (SHM) in baseline spectral‐domain OCT (SD‐OCT) had significantly more visual improvement than eyes without SHM at month 6 (p = 0.007) and had a trend of more visual improvement than eyes without SHM (p = 0.058) at month 12. Eyes with subretinal fluid (SRF) at baseline had significantly more central retinal thickness (CRT) decrease than patients without SRF at month 6 and 12 (p = 0.012 and 0.006 respectively). In univariate regression analysis, dome‐shaped macula (DSM), SRF in baseline OCT image and fuzzy border of mCNV when entering pro re nata (PRN) injection protocol tended to have higher risk of disease recurrence in 1 year (odds ratio: 14.86 (p = 0.003), 3.75 (p = 0.049) and 22.92 (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2410-8650
1607-551X
Relation: https://doaj.org/toc/1607-551X; https://doaj.org/toc/2410-8650
DOI: 10.1002/kjm2.12669
URL الوصول: https://doaj.org/article/ff43fac5e4cd4ff994214e0ca9252aed
رقم الأكسشن: edsdoj.ff43fac5e4cd4ff994214e0ca9252aed
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:24108650
1607551X
DOI:10.1002/kjm2.12669