Zinc, copper, and nitrogen balances during bed rest and fluoride supplementation in healthy adult males

التفاصيل البيبلوغرافية
العنوان: Zinc, copper, and nitrogen balances during bed rest and fluoride supplementation in healthy adult males
المؤلفون: Krebs, J. M, Schneider, V. S, LeBlanc, A. D
المصدر: The American journal of clinical nutrition. 47(3)
بيانات النشر: United States: NASA Center for Aerospace Information (CASI), 1988.
سنة النشر: 1988
مصطلحات موضوعية: Life Sciences (General)
الوصف: The effects of bed rest and fluoride supplementation on zinc, copper, and nitrogen balances and Zn and Cu serum levels were measured in 15 healthy males. Subjects aged 19-54 y remained on a metabolic research ward for 10 wk. During weeks 1-5, subjects were ambulatory. During wks 6-10 they remained in continuous bed rest. During weeks 3-10 nine subjects received 10 or 20 mg F/d as sodium fluoride. Daily urine and weekly fecal composites were made and biweekly fasting blood samples were taken. Dietary intakes were 1.40 +/- 0.17 mg Cu/d (22.0 +/- 2.7 mumol Cu/d), 10.82 +/- 0.49 mg Zn/d (165.6 +/- 7.6 mumol Zn/d), and 14.27 +/- 0.23 g N/d (1019 +/- 16 mmol N/d). Bed rest increased urinary Zn and N excretions and fecal Zn excretions and decreased Zn balance (p less than 0.05) whereas Cu balance was unchanged. During bed rest, F supplementation increased Zn and N balances compared with untreated control subjects (p less than 0.05). These results are compatible with bone and muscle atrophy during bed rest and increased bone formation with F supplementation.
نوع الوثيقة: Report
اللغة: English
تدمد: 0002-9165
URL الوصول: https://ntrs.nasa.gov/citations/20050037260
ملاحظات: RR02558

RR00350
رقم الأكسشن: edsnas.20050037260
قاعدة البيانات: NASA Technical Reports