مورد إلكتروني
Ovarian tissue cryopreservation and transplantation among alternatives for fertility preservation in the Nordic countries - compilation of 20 years of multicenter experience
| العنوان: | Ovarian tissue cryopreservation and transplantation among alternatives for fertility preservation in the Nordic countries - compilation of 20 years of multicenter experience |
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| المؤلفون: | Rodriguez-Wallberg, Kenny A., Tanbo, Tom, Tinkanen, Helena, Thurin-Kjellberg, Ann, Nedstrand, Elisabeth, Laczna Kitlinski, Margareta, Macklon, Kirsten T., Ernst, Erik, Fedder, Jens, Tiitinen, Aila, Morin-Papunen, Laure, Einarsson, Snorri, Jokimaa, Varpu, Hippelainen, Maritta, Lood, Mikael, Gudmundsson, Johannes, Olofsson, Jan I., Yding Andersen, Claus |
| بيانات النشر: | Linköpings universitet, Avdelningen för kliniska vetenskaper Linköpings universitet, Hälsouniversitetet Region Östergötland, Kvinnokliniken i Linköping Karolinska University Hospital, Sweden; Karolinska Institute, Sweden Department of Gynecology, Oslo University Hospital, Oslo, Norway Oslo University Hospital, Norway; Tampere University Hospital, Finland Sahlgrens University Hospital, Sweden Skåne University Hospital, Sweden Rigshosp University Hospital, Denmark Aarhus University Hospital, Denmark Odense University Hospital, Denmark Helsinki University Hospital, Finland Oulu University Hospital, Finland; University of Oulu, Finland ART Medica, Iceland Turku University Hospital, Finland Kuopio University Hospital, Finland Örebro University Hospital, Sweden University of Uppsala Hospital, Sweden Karolinska University Hospital, Sweden; Karolinska Institute, Sweden Rigshosp University Hospital, Denmark; University of Copenhagen, Denmark WILEY-BLACKWELL 2016 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Introduction. The aim of this study is to report the current status of ovarian tissue cryopreservation among alternatives for fertility preservation in the Nordic countries. Material and methods. A questionnaire was sent to 14 Nordic academic reproductive centers with established fertility preservation programs. It covered fertility preservation cases performed up to December 2014, standard procedures for ovarian tissue cryopreservation and oocyte cryopreservation and reproductive outcomes following ovarian tissue transplantation. Results. Among the Nordic countries, Denmark and Norway practice ovarian tissue cryopreservation as a clinical treatment (822 and 164 cases, respectively) and their programs are centralized. In Sweden (457 cases), ovarian tissue cryopreservation is practiced at five of six centers and in Finland at all five centers (145 cases). Nearly all considered ovarian tissue cryopreservation to be experimental. In Iceland, embryo cryopreservation is the only option for fertility preservation. Most centers use slow-freezing methods for ovarian tissue cryopreservation. Most patients selected for ovarian tissue cryopreservation were newly diagnosed with cancer and the tissue was predominantly retrieved laparoscopically by unilateral oophorectomy. Only minor complications were reported. In total, 46 women have undergone ovarian tissue transplantation aiming at recovering fertility, 17 healthy children have been born and several additional pregnancies are currently ongoing. Whenever patients clinical condition is permissive, oocyte cryopreservation after hormonal stimulation is preferred for fertility preservation. Between 2012 and 2014, a smaller proportion of females have undergone fertility preservation in the Nordic centers, in comparison to males (1: 3). Conclusions. Overall, ovarian tissue cryopreservation was reported to be safe. Slow freezing methods are still preferred. Promising results of recovery of fertility have been reported in Nordic count Funding Agencies|Swedish Research Council; Stockholm County Council |
| مصطلحات الفهرس: | Cancer; female; fertility preservation; oocytes; ovarian tissue cryopreservation; ovarian transplantation, Obstetrics, Gynecology and Reproductive Medicine, Reproduktionsmedicin och gynekologi, Article in journal, info:eu-repo/semantics/article, text |
| DOI: | 10.1111.aogs.12934 |
| URL: | Acta Obstetricia et Gynecologica Scandinavica, 0001-6349, 2016, 95:9, s. 1015-1026 |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | UPE oai:DiVA.org:liu-132864 doi:10.1111/aogs.12934 PMID 27258933 ISI:000386782100009 1233546553 |
| المصدر المساهم: | UPPSALA UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1233546553 |
| قاعدة البيانات: | OAIster |
| DOI: | 10.1111.aogs.12934 |
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