مورد إلكتروني
Exploring the protein–protein interaction landscape in plants
| العنوان: | Exploring the protein–protein interaction landscape in plants |
|---|---|
| المؤلفون: | Ministerio de Economía y Competitividad (España), European Commission, Research Foundation - Flanders, Struk, Sylwia, Jacobs, Anse, Sánchez Martín‐Fontecha, Elena, Gevaert, Kris, Cubas Domínguez, Pilar, Goormachtig, Sofie |
| بيانات النشر: | John Wiley & Sons 2019-02 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Protein–protein interactions (PPIs) represent an essential aspect of plant systems biology. Identification of key protein players and their interaction networks provide crucial insights into the regulation of plant developmental processes and into interactions of plants with their environment. Despite the great advance in the methods for the discovery and validation of PPIs, still several challenges remain. First, the PPI networks are usually highly dynamic, and the in vivo interactions are often transient and difficult to detect. Therefore, the properties of the PPIs under study need to be considered to select the most suitable technique, because each has its own advantages and limitations. Second, besides knowledge on the interacting partners of a protein of interest, characteristics of the interaction, such as the spatial or temporal dynamics, are highly important. Hence, multiple approaches have to be combined to obtain a comprehensive view on the PPI network present in a cell. Here, we present the progress in commonly used methods to detect and validate PPIs in plants with a special emphasis on the PPI features assessed in each approach and how they were or can be used for the study of plant interactions with their environment. |
| مصطلحات الفهرس: | Protein–protein interaction techniques, Plant interactome, Signal transduction pathway, Plant‐environment interactions, Co‐complex purification, Binary methods, artículo de revisión |
| URL: | Sí info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BIO2014‐57011‐R |
| الإتاحة: | Open access content. Open access content closedAccess |
| أرقام أخرى: | CTK oai:digital.csic.es:10261/240341 Plant, Cell and Environment 42(2): 387-409 (2019) 10.1111/pce.13433 1286572412 |
| المصدر المساهم: | CSIC From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1286572412 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |