مورد إلكتروني
Long-term outcomes of patients with cerebral vein thrombosis: a multicenter study
| العنوان: | Long-term outcomes of patients with cerebral vein thrombosis: a multicenter study |
|---|---|
| المؤلفون: | Dentali, F, Poli, D, Scoditti, U, Di Minno, M, De Stefano, V, Stefano, V, Siragusa, S, Kostal, M, Palareti, G, Sartori, M, Grandone, E, Vedovati, M, Ageno, W, Falanga, A, Lerede, T, Bianchi, M, Testa, S, Witt, D, Mccool, K, Bucherini, E, Grifoni, E, Coalizzo, D, Benedetti, R, Marietta, M, Sessa, M, Guaschino, C, di Minno, G, Tufano, A, Barbar, S, Malato, A, Pini, M, Castellini, P, Barco, S, Barone, M, Paciaroni, M, Alberti, A, Agnelli, G, Giorgi Pierfranceschi, M, Dulicek, P, Silingardi, M, Federica, L, Ghirarduzzi, A, Tiraferri, E, di Lazzaro, V, Rossi, E, Ciminello, A, Pasca, S, Barillari, G, Rezoagli, E, Galli, M, Squizzato, A, Tosetto, A, Di Minno, M N D, Stefano, V D, Sartori, M T, Vedovati, M C, Falanga, Anna, Lerede, Teresa, Bianchi, Marina, Testa, Sophie, Witt, Dan, McCool, Katie, Bucherini, Eugenio, Grifoni, Elisa, Coalizzo, Daniela, Benedetti, Raffaella, Marietta, Marco, Sessa, Maria, Guaschino, Clara, di Minno, Giovanni, Tufano, Antonella, Barbar, Sofia, Malato, Alessandra, Pini, Mario, Castellini, Paola, Barco, Stefano, Barone, Marisa, Paciaroni, Maurizio, Alberti, Andrea, Agnelli, Giancarlo, Giorgi Pierfranceschi, Matteo, Dulicek, Petr, Silingardi, Mauro, Federica, Landini, Ghirarduzzi, Angelo, Tiraferri, Eros, di Lazzaro, Vincenzo, Rossi, Elena, Ciminello, Angela, Pasca, Samantha, Barillari, Giovanni, Rezoagli, Emanuele, Galli, Matteo, Squizzato, Alessandro, Tosetto, Alberto |
| بيانات النشر: | Wiley-Blackwell 2012 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Background: Little information is available on the long-term clinical outcome of cerebral vein thrombosis (CVT). Objectives and methods: In an international, retrospective cohort study, we assessed the long-term rates of mortality, residual disability and recurrent venous thromboembolism (VTE) in a cohort of patients with a first CVT episode. Results: Seven hundred and six patients (73.7% females) with CVT were included. Patients were followed for a total of 3171 patient-years. Median follow-up was 40months (range 6, 297months). At the end of follow-up, 20 patients had died (2.8%). The outcome was generally good: 89.1% of patients had a complete recovery (modified Rankin Score [mRS] 0-1) and 3.8% had a partial recovery and were independent (mRS 2). Eighty-four per cent of patients were treated with oral anticoagulants and the mean treatment duration was 12months. CVT recurred in 31 patients (4.4%), and 46 patients (6.5%) had a VTE in a different site, for an overall incidence of recurrence of 23.6 events per 1000 patient-years (95% confidence Interval [CI] 17.8, 28.7) and of 35.1 events/1000 patient-years (95% CI, 27.7, 44.4) after anticoagulant therapy withdrawal. A previous VTE was the only significant predictor of recurrence at multivariate analysis (hazard ratio [HR] 2.70; 95% CI 1.25, 5.83). Conclusions: The long-term risk of mortality and recurrent VTE appears to be low in patients who survived the acute phase of CVT. A previous VTE history independently predicts recurrent events. |
| مصطلحات الفهرس: | Adult, Cerebral Vein thrombosi, Cohort Studie, Female, Human, Male, Middle Aged, Recurrence, Thrombosis, MED/41 - ANESTESIOLOGIA, info:eu-repo/semantics/article |
| URL: | info:eu-repo/semantics/altIdentifier/pmid/22578023 info:eu-repo/semantics/altIdentifier/wos/WOS:000305979300011 volume:10 issue:7 firstpage:1297 lastpage:1302 numberofpages:6 journal:JOURNAL OF THROMBOSIS AND HAEMOSTASIS |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | ELETTRONICO English |
| أرقام أخرى: | ITBAO oai:boa.unimib.it:10281/287242 10.1111/j.1538-7836.2012.04774.x info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84863449597 1308936210 |
| المصدر المساهم: | BICOCCA OPEN ARCH From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1308936210 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |