مورد إلكتروني
Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells
| العنوان: | Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells |
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| المؤلفون: | Hyun, I, Munsie, M, Pera, MF, Rivron, NC, Rossant, J |
| بيانات النشر: | CELL PRESS 2020-02-11 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Over the past few years, a number of research groups have reported striking progress on the generation of in vitro models from mouse and human stem cells that replicate aspects of early embryonic development. Not only do these models reproduce some key cell fate decisions but, especially in the mouse system, they also mimic the spatiotemporal arrangements of embryonic and extraembryonic tissues that are required for developmental patterning and implantation in the uterus. If such models could be developed for the early human embryo, they would have great potential benefits for understanding early human development, for biomedical science, and for reducing the use of animals and human embryos in research. However, guidelines for the ethical conduct of this line of work are at present not well defined. In this Forum article, we discuss some key aspects of this emerging area of research and provide some recommendations for its ethical oversight. |
| مصطلحات الفهرس: | Journal Article |
| URL: | |
| الإتاحة: | Open access content. Open access content CC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0 |
| أرقام أخرى: | UMV oai:jupiter.its.unimelb.edu.au:11343/247475 Hyun, I., Munsie, M., Pera, M. F., Rivron, N. C. & Rossant, J. (2020). Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells. STEM CELL REPORTS, 14 (2), pp.169-174. https://doi.org/10.1016/j.stemcr.2019.12.008. 10.1016/j.stemcr.2019.12.008 2213-6711 2213-6711 1315713510 |
| المصدر المساهم: | UNIV OF MELBOURNE From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1315713510 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |