مورد إلكتروني
WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases
| العنوان: | WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases |
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| المؤلفون: | Carey, Jannette, Brynda, Jiri, Wolfová, Julie, Grandori, Rita, Gustavsson, Tobias, Ettrich, Rüdiger, Smatanová, Ivana Kutá |
| المصدر: | Carey , J , Brynda , J , Wolfová , J , Grandori , R , Gustavsson , T , Ettrich , R & Smatanová , I K 2007 , ' WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases ' , Protein Science , vol. 16 , no. 10 , pp. 2301-5 . |
| بيانات النشر: | 2007-10 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | The crystal structure of the flavodoxin-like protein WrbA with oxidized FMN bound reveals a close relationship to mammalian NAD(P)H:quinone oxidoreductase, Nqo1. Structural comparison of WrbA, flavodoxin, and Nqo1 indicates how the twisted open-sheet fold of flavodoxins is elaborated to form multimers that extend catalytic function from one-electron transfer between protein partners using FMN to two-electron reduction of xenobiotics using FAD. The structure suggests a novel physiological role for WrbA and Nqo1. |
| مصطلحات الفهرس: | Binding Sites, DNA-Binding Proteins/chemistry, Escherichia coli Proteins/chemistry, Flavodoxin/chemistry, Models, Molecular, NAD(P)H Dehydrogenase (Quinone)/chemistry, Protein Folding, Repressor Proteins/chemistry, article |
| URL: | |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/restrictedAccess |
| ملاحظة: | English |
| أرقام أخرى: | DAV oai:pure.atira.dk:publications/18c4fdfa-108e-41c0-ac56-5986317e7f43 1318942753 |
| المصدر المساهم: | UNIV OF COPENHAGEN From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1318942753 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |