مورد إلكتروني
Ethical considerations regarding animal experimentation
| العنوان: | Ethical considerations regarding animal experimentation |
|---|---|
| المصدر: | Journal of Preventive Medicine and Hygiene; Vol. 63 No. 2S3 (2022): The secret of Mediterranean food: How “omic” sciences, biochemistry and human physiology can be applied to exploit the secrets of Mediterranean foods; E255; 2421-4248; 1121-2233; 10.15167/2421-4248/jpmh2022.63.2S3 |
| بيانات النشر: | Department of Health Science - University of Genoa 2022-10-17 |
| تفاصيل مُضافة: | Kiani, Aysha Karim Pheby, Derek Henehan, Gary Brown, Richard Sieving, Paul Sykora, Peter Marks, Robert Falsini, Benedetto Capodicasa, Natale Miertus , Stanislav Lorusso, Lorenzo Dondossola, Daniele Tartaglia, Gianluca Martino Ergoren, Mahmut Cerkez Dundar, Munis Michelini, Sandro Malacarne, Daniele Bonetti, Gabriele Dautaj, Astrit Donato, Kevin Medori , Maria Chiara Beccari, Tommaso Samaja, Michele Connelly, Stephen Thaddeus Martin, Donald Morresi, Assunta Bacu, Ariola Herbst, Karen L. Kapustin, Mykhaylo Stuppia, Liborio Lumer, Ludovica Farronato, Giampietro Bertelli, Matteo |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Animal experimentation is widely used around the world for the identification of the root causes of various diseases in humans and animals and for exploring treatment options. Among the several animal species, rats, mice and purpose-bred birds comprise almost 90% of the animals that are used for research purpose. However, growing awareness of the sentience of animals and their experience of pain and suffering has led to strong opposition to animal research among many scientists and the general public. In addition, the usefulness of extrapolating animal data to humans has been questioned. This has led to Ethical Committees’ adoption of the ‘four Rs’ principles (Reduction, Refinement, Replacement and Responsibility) as a guide when making decisions regarding animal experimentation. Some of the essential considerations for humane animal experimentation are presented in this review along with the requirement for investigator training. Due to the ethical issues surrounding the use of animals in experimentation, their use is declining in those research areas where alternative in vitro or in silico methods are available. However, so far it has not been possible to dispense with experimental animals completely and further research is needed to provide a road map to robust alternatives before their use can be fully discontinued. |
| مصطلحات الفهرس: | Animal experimentation, Animal model, Bioethics, 4Rs principle, Animal welfare, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion |
| URL: | |
| الإتاحة: | Open access content. Open access content Copyright (c) 2022 Journal of Preventive Medicine and Hygiene |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | ITDHS oai:ojs.pkp.sfu.ca:article/2768 1352898331 |
| المصدر المساهم: | DEPARTMENT OF HEALTH SCIENCES From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1352898331 |
| قاعدة البيانات: | OAIster |
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