مورد إلكتروني
A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue
العنوان: | A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue |
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المؤلفون: | (0000-0002-3201-6002) Petr, J., Hogeboom, L., (0000-0002-4568-4018) Nikulin, P., Wiegers, E., Schroyen, G., Kallehauge, J., Chmelik, M., Clement, P., Nechifor, R. E., Fodor, L.-A., Witt Hamer, P., Barkhof, F., Pernet, C., Lequin, M., Deprez, S., Jancalek, R., Mutsaerts, H. J., Pizzini, F. B., Emblem, K. E., Keil, V. C. |
المصدر: | Magnetic Resonance Materials in Physics, Biology and Medicine 35(2022), 163-186 |
بيانات النشر: | 2022 |
نوع الوثيقة: | Electronic Resource |
مستخلص: | Cancer therapy for both central nervous system (CNS) and non-CNS tumors has been previously associated with transient and long-term cognitive deterioration, commonly referred to as ‘chemo fog’. This therapy-related damage to otherwise normal-appearing brain tissue is reported using post-mortem neuropathological analysis. Although the literature on monitoring therapy effects on structural magnetic resonance imaging (MRI) is well-established, such macroscopic structural changes appear relatively late and irreversible. Early quantitative MRI biomarkers of therapy-induced damage would potentially allow to take these treatment side-effects into account and pave the way towards a more personalized treatment planning. This systematic review (PROSPERO number 224196) provides an overview of quantitative tomographic imaging methods, potentially identifying the adverse side-effects of cancer therapy in normal-appearing brain tissue. Sixty-six studies were obtained from the MEDLINE and Web of Science databases. Studies reporting changes in normal-appearing brain tissue using MRI, PET, or SPECT quantitative biomarkers, related to radio-, chemo-, immuno-, or hormone therapy for any kind of solid, cystic, or liquid tumor were included. The reviewed studies were assessed for risk of bias using a modified QUADAS-2 tool, of which findings were summarized. For each imaging method, this review provides the methodological background, and the benefits and shortcomings of each method from the imaging perspective. Finally, a set of recommendations is proposed to support future research. |
مصطلحات الفهرس: | info:eu-repo/semantics/publishedVersion, doc-type:article, Text |
URL: | info:eu-repo/semantics/reference/doi/10.1007/s10334-021-00985-2 info:eu-repo/semantics/altIdentifier/purl/https://www.hzdr.de/publications/Publ-33109-1 |
الإتاحة: | Open access content. Open access content Open Access |
ملاحظة: | application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document English |
أرقام أخرى: | DERBS HZDR:PUBLDB:33109-1 1415626269 |
المصدر المساهم: | ROBIS REPOSITORY From OAIster®, provided by the OCLC Cooperative. |
رقم الأكسشن: | edsoai.on1415626269 |
قاعدة البيانات: | OAIster |
الوصف غير متاح. |