مورد إلكتروني
Reply to: Re-evaluating evidence for adaptive mutation rate variation
| العنوان: | Reply to: Re-evaluating evidence for adaptive mutation rate variation |
|---|---|
| المؤلفون: | University of California, Davis, Monroe, J. Grey, Murray, Kevin D., Xian, Wenfei, Srikant, Thanvi, Carbonell-Bejerano, Pablo, Becker, Claude, Lensink, Mariele, Exposito-Alonso, Moises, Klein, Marie, Hildebrandt, Julia, Neumann, Manuela, Kliebenstein, Daniel, Weng, Mao-Lun, Imbert, Eric, Ågren, Jon, Rutter, Matthew T., Fenster, Charles B., Weigel, Detlef |
| بيانات النشر: | Nature Publishing Group 2023-07 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Wang and colleagues1 argue that our report2 of lower mutation rates in gene bodies, essential genes and regions marked by H3K4me1 must result from DNA sequencing errors. We appreciate the issues raised by them and by other colleagues3. Although we overlooked some sources of errors, these are insufficient to invalidate our conclusions, which are confirmed by more stringent reanalyses of our original data, new analyses restricted to high-confidence germline mutations4, and direct demonstration of plant DNA repair proteins being recruited to gene bodies, essential genes and H3K4me1, where they reduce local mutation rates5,6. |
| مصطلحات الفهرس: | artículo |
| URL: | Publisher's version The underlying dataset has been published as supplementary material of the article in the publisher platform at http://dx.doi.org/10.1038/s41586-023-06315-x Sí |
| الإتاحة: | Open access content. Open access content http://creativecommons.org/licenses/by/4.0 openAccess |
| ملاحظة: | English |
| أرقام أخرى: | CTK oai:digital.csic.es:10261/352881 Nature 619: E57–E60 (2023) 0028-0836 10.1038/s41586-023-06315-x 1476-4687 37495874 2-s2.0-85165689300 1431965583 |
| المصدر المساهم: | CSIC From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1431965583 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |