دورية أكاديمية
Kidney donation after circulatory death in a country with a high number of brain dead donors: 10 -year experience in Belgium
| العنوان: | Kidney donation after circulatory death in a country with a high number of brain dead donors: 10 -year experience in Belgium |
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| المؤلفون: | Jochmans, Ina, Darius, Tom, Kuypers, Dirk, Monbaliu, Diethard, Goffin, Eric, Mourad, Michel, Ledinh, Hieu, WEEKERS, Laurent, Peeters, Patrick, Randon, Caren, Bosmans, Jean-Louis, Roeyen, Geert, Abramowicz, Daniel, Hoang, Anh-Dung, De Pauw, Luc, Rahmel, Axel, SQUIFFLET, Jean-Paul, Pirenne, Jacques |
| المصدر: | Transplant International, 25, 857-866 (2012) |
| بيانات النشر: | Springer International, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | belgium, delayed graft function, donation after circulatory death, donation programs, kidney transplantation, risk factors, Human health sciences, Surgery, Sciences de la santé humaine, Chirurgie |
| الوصف: | Worldwide shortage of standard brain dead donors (DBD) has revived the useof kidneys donated after circulatory death (DCD). We reviewed the BelgianDCD kidney transplant (KT) experience since its reintroduction in 2000. Riskfactors for delayed graft function (DGF) were identified using multivariateanalysis. Five-year patient/graft survival was assessed using Kaplan–Meiercurves. The evolution of the kidney donor type and the impact of DCDs onthe total KT activity in Belgium were compared with the Netherlands. Between2000 and 2009, 287 DCD KT were performed. Primary nonfunction occurredin 1% and DGF in 31%. Five-year patient and death-censored graft survivalwere 93% and 95%, respectively. In multivariate analysis, cold storage (versusmachine perfusion), cold ischemic time, and histidine-tryptophan-ketoglutaratesolution were independent risk factors for the development of DGF. Despite anincreased number of DCD donations and transplantations, the total number ofdeceased KT did not increase significantly. This could suggest a shift fromDBDs to DCDs. To increase KT activity, Belgium should further expand controlledDCD programs while simultaneously improve the identification of allpotential DBDs and avoid their referral for donation as DCDs before braindeath occurs. Furthermore, living donation remains underused.Transplant International ISSN 0934-0874ª |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article |
| اللغة: | English |
| Relation: | urn:issn:0934-0874; urn:issn:1432-2277 |
| DOI: | 10.1111/j.1432-2277.2012.01510.x |
| URL الوصول: | https://orbi.uliege.be/handle/2268/129453 |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess |
| رقم الأكسشن: | edsorb.129453 |
| قاعدة البيانات: | ORBi |
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