دورية أكاديمية
Glomerular hyperfiltration: part 2-clinical significance in children.
| العنوان: | Glomerular hyperfiltration: part 2-clinical significance in children. |
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| المؤلفون: | Adebayo, Oyindamola C, Nkoy, Agathe B, van den Heuvel, Lambertus P, Labarque, Veerle, Levtchenko, Elena, Delanaye, Pierre, Pottel, Hans |
| المصدر: | Pediatric Nephrology, 38 (8), 2529 - 2547 (2023-08) |
| بيانات النشر: | Springer Science and Business Media Deutschland GmbH, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Autosomal dominant polycystic kidney disease (ADPKD), Diabetic kidney disease, Duchenne muscular dystrophy, Glomerular hyperfiltration, Obesity-related glomerulopathy, Pediatric population, Sickle cell disease, Solitary functioning kidney, Pediatrics, Perinatology and Child Health, Nephrology, Human health sciences, Urology & nephrology, Sciences de la santé humaine, Urologie & néphrologie |
| الوصف: | Glomerular hyperfiltration (GHF) is a phenomenon that can occur in various clinical conditions affecting the kidneys such as sickle cell disease, diabetes mellitus, autosomal dominant polycystic kidney disease, and solitary functioning kidney. Yet, the pathophysiological mechanisms vary from one disease to another and are not well understood. More so, it has been demonstrated that GHF may occur at the single-nephron in some clinical conditions while in others at the whole-kidney level. In this review, we explore the pathophysiological mechanisms of GHF in relation to various clinical conditions in the pediatric population. In addition, we discuss the role and mechanism of action of important factors such as gender, low birth weight, and race in the pathogenesis of GHF. Finally, in this current review, we further highlight the consequences of GHF in the progression of kidney disease. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article peer reviewed |
| اللغة: | English |
| Relation: | https://link.springer.com/content/pdf/10.1007/s00467-022-05826-5.pdf; urn:issn:0931-041X; urn:issn:1432-198X |
| DOI: | 10.1007/s00467-022-05826-5 |
| URL الوصول: | https://orbi.uliege.be/handle/2268/305570 |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess |
| رقم الأكسشن: | edsorb.305570 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1007/s00467-022-05826-5 |
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