دورية أكاديمية
The Association between Epilepsy and Autism Symptoms and Maladaptive Behaviors in Children with Autism Spectrum Disorder
| العنوان: | The Association between Epilepsy and Autism Symptoms and Maladaptive Behaviors in Children with Autism Spectrum Disorder |
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| اللغة: | English |
| المؤلفون: | Viscidi, Emma W., Johnson, Ashley L., Spence, Sarah J., Buka, Stephen L., Morrow, Eric M., Triche, Elizabeth W. |
| المصدر: | Autism: The International Journal of Research and Practice. Nov 2014 18(8):996-1006. |
| الإتاحة: | SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com |
| Peer Reviewed: | Y |
| Page Count: | 11 |
| تاريخ النشر: | 2014 |
| Sponsoring Agency: | National Institutes of Health (DHHS) |
| Contract Number: | P20 GM103645-01 |
| نوع الوثيقة: | Journal Articles Reports - Research |
| Descriptors: | Symptoms (Individual Disorders), Autism, Pervasive Developmental Disorders, Epilepsy, Correlation, Children, Comorbidity, Behavior Problems, Intelligence Quotient, Hyperactivity, Comparative Analysis, Mental Retardation, Severity (of Disability), Asperger Syndrome, Clinics, At Risk Persons |
| Assessment and Survey Identifiers: | Aberrant Behavior Checklist, Mullen Scales of Early Learning, Autism Diagnostic Observation Schedule, Wechsler Intelligence Scale for Children |
| DOI: | 10.1177/1362361313508027 |
| تدمد: | 1362-3613 |
| مستخلص: | Epilepsy is common in children with autism spectrum disorder (ASD) but little is known about how seizures impact the autism phenotype. The association between epilepsy and autism symptoms and associated maladaptive behaviors was examined in 2,645 children with ASD, of whom 139 had epilepsy, from the Simons Simplex Collection. Children with ASD and epilepsy had significantly more autism symptoms and maladaptive behaviors than children without epilepsy. However, after adjusting for IQ, only hyperactivity symptoms remained significantly increased (13% higher) in the epilepsy group. Among children with ASD without co-occurring intellectual disability, children with epilepsy had significantly more irritability (20% higher) and hyperactivity (24% higher) symptoms. This is the largest study to date comparing the autism phenotype in children with ASD with and without epilepsy. Children with ASD and epilepsy showed greater impairment than children without epilepsy, which was mostly explained by the lower IQ of the epilepsy group. These findings have important clinical implications for patients with ASD. |
| Abstractor: | As Provided |
| Number of References: | 60 |
| Entry Date: | 2014 |
| رقم الأكسشن: | EJ1042953 |
| قاعدة البيانات: | ERIC |
Full Text Finder | تدمد: | 1362-3613 |
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| DOI: | 10.1177/1362361313508027 |