دورية أكاديمية
Pilot Study of Respiratory-Swallow Coordination in Amyotrophic Lateral Sclerosis
| العنوان: | Pilot Study of Respiratory-Swallow Coordination in Amyotrophic Lateral Sclerosis |
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| اللغة: | English |
| المؤلفون: | Garand, Kendrea L. (ORCID |
| المصدر: | Journal of Speech, Language, and Hearing Research. Aug 2022 65(8):2815-2828. |
| الإتاحة: | American Speech-Language-Hearing Association. 2200 Research Blvd #250, Rockville, MD 20850. Tel: 301-296-5700; Fax: 301-296-8580; e-mail: slhr@asha.org; Web site: http://jslhr.pubs.asha.org |
| Peer Reviewed: | Y |
| Page Count: | 14 |
| تاريخ النشر: | 2022 |
| نوع الوثيقة: | Journal Articles Reports - Research |
| Descriptors: | Neurological Impairments, Motor Reactions, Physical Disabilities, Physiology, Adults, Psychomotor Skills |
| DOI: | 10.1044/2022_JSLHR-21-00619 |
| تدمد: | 1092-4388 1558-9102 |
| مستخلص: | Purpose: Amyotrophic lateral sclerosis (ALS) impacts bulbar and respiratory musculature, which may contribute to impaired swallow function (dysphagia) and respiratory-swallow coordination. The purpose of this pilot study was to examine if respiratory-swallow coordination in individuals with ALS was perturbed compared to healthy controls. We further explored relationships between measures of respiratory function and self-reported swallowing outcomes on respiratory-swallow coordination. Method: We employed a cross-sectional design with eight participants with ALS and eight age- and sex-matched healthy participants. Respiratory inductance plethysmography and a nasal cannula were used to capture respiratory-swallow phase patterns during a standardized clinical swallow examination. The advantageous respiratory-swallow phase pattern was defined if exhalation surrounded the swallow (E-E). Spirometry was used to capture indices of respiratory function (forced vital capacity % predicted, peak cough flow [PCF]). Validated questionnaires were used to collect information regarding ALS-related bulbar functional status and swallowing-related concerns. Results: Compared to the matched healthy cohort, individuals with ALS demonstrated higher rates of non-E-E respiratory-swallow phase patterning and worse bulbar/swallow dysfunction. Group (ALS), swallow tasks, and PCF were significantly associated with respiratory-swallow phase pattern. Conclusions: These preliminary findings support altered respiratory-swallow phase patterning in ALS. Future work should employ an instrumental assessment to quantify swallowing physiology and elucidate the relationship between perturbed respiratory-swallow coordination and swallowing function. |
| Abstractor: | As Provided |
| Entry Date: | 2023 |
| رقم الأكسشن: | EJ1360736 |
| قاعدة البيانات: | ERIC |
Full Text Finder | تدمد: | 1092-4388 1558-9102 |
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| DOI: | 10.1044/2022_JSLHR-21-00619 |