دورية أكاديمية
Retinal Thinning in Adults with Autism Spectrum Disorder
| العنوان: | Retinal Thinning in Adults with Autism Spectrum Disorder |
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| اللغة: | English |
| المؤلفون: | Evelyn B. N. Friedel, Ludger Tebartz van Elst, Mirjam Schäfer, Simon Maier, Kimon Runge, Sebastian Küchlin, Michael Reich, Wolf A. Lagrèze, Jürgen Kornmeier, Dieter Ebert, Dominique Endres, Katharina Domschke, Kathrin Nickel (ORCID |
| المصدر: | Journal of Autism and Developmental Disorders. 2024 54(3):1143-1156. |
| الإتاحة: | Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Peer Reviewed: | Y |
| Page Count: | 14 |
| تاريخ النشر: | 2024 |
| نوع الوثيقة: | Journal Articles Reports - Research |
| Descriptors: | Human Body, Autism Spectrum Disorders, Adults, Severity (of Disability), Neurology, Diagnostic Tests |
| Assessment and Survey Identifiers: | Social Responsiveness Scale |
| DOI: | 10.1007/s10803-022-05882-8 |
| تدمد: | 0162-3257 1573-3432 |
| مستخلص: | Since the retina shares its embryological origin with the central nervous system, optical coherence tomography (OCT), an imaging technique frequently employed in ophthalmology to analyze the macula and intraretinal layer thicknesses and volumes, has recently become increasingly important in psychiatric research. We examined 34 autistic and 31 neurotypical adults (NT) using OCT. Autistic adults had reduced overall macular and outer nuclear layer (ONL) thickness and volume compared to NT. Both macular and ONL thickness showed significant inverse associations with the severity of autistic symptoms measured with the Social Responsiveness Scale 2 (SRS-2). Longitudinal studies across different age groups are required to clarify whether retinal changes may represent a possible trait marker. |
| Abstractor: | As Provided |
| Entry Date: | 2024 |
| رقم الأكسشن: | EJ1415144 |
| قاعدة البيانات: | ERIC |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 0162-3257 1573-3432 |
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| DOI: | 10.1007/s10803-022-05882-8 |