دورية أكاديمية
Aortic stenosis. Gender influence on left ventricular geometry and function in patients under 70 years of age.
| العنوان: | Aortic stenosis. Gender influence on left ventricular geometry and function in patients under 70 years of age. |
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| المؤلفون: | da Rocha AS; Hospital de Cardiologia de Laranjeiras, Ministério da Saúde-Rio de Janeiro, Brazil., Pereira MA, Rocha Nde N, Soares Rde C, Garcia C, Grandelle R, da Silva PR |
| المصدر: | Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 1999 Apr; Vol. 72 (4), pp. 475-82. |
| نوع المنشور: | Journal Article |
| اللغة: | English; Portuguese |
| بيانات الدورية: | Publisher: Sociedad Brasileira De Cardiologia Country of Publication: Brazil NLM ID: 0421031 Publication Model: Print Cited Medium: Print ISSN: 0066-782X (Print) Linking ISSN: 0066782X NLM ISO Abbreviation: Arq Bras Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Sao Paulo : Sociedad Brasileira De Cardiologia |
| مواضيع طبية MeSH: | Aortic Valve Stenosis/*physiopathology , Ventricular Function, Left/*physiology, Adult ; Female ; Heart Ventricles/anatomy & histology ; Humans ; Male ; Middle Aged ; Sex Factors |
| مستخلص: | Objective: To verify if adaptive left ventricle (LV) characteristics are also present in individuals under 70 years of age with severe aortic stenosis (AS). Methods: The study comprised 40 consecutive patients under 70 years of age with AS and no associated coronary artery disease, referred for valve surgery. Out of the 40 patients, 22 were men and 18 women, and the mean age was 49.8 +/- 14.3 years. Cardiac symptoms, presence of systemic hypertension (SH), functional class according to the New York Heart Association (NYHA), and valve lesion etiology were considered. LV cavity dimensions, ejection fraction (EF), fractional shortening (FS), mass (MS), and relative diastolic thickness (RDT) were examined by Doppler echocardiography. Results: Fourteen (63.6%) men and 11 (61.6%) women were classified as NYHA class III/IV (p = 0.70). There was no difference in the frequency of angina, syncope or dyspnea between genders. The incidence of SH was greater in women than in men (10 versus 2, p = 0.0044). Women had a smaller LV end-diastolic diameter index (32.1 +/- 6.5 x 36.5 +/- 5.3 mm/m2, p = 0.027), LV end-systolic diameter index (19.9 +/- 5.9 x 26.5 +/- 6.4 mm/m2, p = 0.0022) and LV mass index (MS) (211.4 +/- 71.1 x 270.9 +/- 74.9 g/m2, p = 0.017) when compared with men. EF (66.2 +/- 13.4 x 52.0 +/- 14.6%, p = 0.0032), FS (37.6 +/- 10.7 x 27.9 +/- 9.6%, p = 0.0046) and RDT (0.58 +/- 0.22 x 0.44 +/- 0.09, p = 0.0095) were significantly greater in women than in men. Conclusion: It is the patient gender rather than age that influences left ventricular adaptive response to AS. |
| تواريخ الأحداث: | Date Created: 19991026 Date Completed: 19991229 Latest Revision: 20190516 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1590/s0066-782x1999000400007 |
| PMID: | 10531691 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0066-782X |
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| DOI: | 10.1590/s0066-782x1999000400007 |