دورية أكاديمية
Risk of papillary thyroid cancer in women in relation to smoking and alcohol consumption.
| العنوان: | Risk of papillary thyroid cancer in women in relation to smoking and alcohol consumption. |
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| المؤلفون: | Rossing MA; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA 98109-1024, USA., Cushing KL, Voigt LF, Wicklund KG, Daling JR |
| المصدر: | Epidemiology (Cambridge, Mass.) [Epidemiology] 2000 Jan; Vol. 11 (1), pp. 49-54. |
| نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9009644 Publication Model: Print Cited Medium: Print ISSN: 1044-3983 (Print) Linking ISSN: 10443983 NLM ISO Abbreviation: Epidemiology Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2000>- : Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: [Cambridge, MA : Blackwell Scientific Publications ; Chestnut Hill, MA : Epidemiology Resources, c1990- |
| مواضيع طبية MeSH: | Alcohol Drinking/*adverse effects , Carcinoma, Papillary/*etiology , Smoking/*adverse effects , Thyroid Neoplasms/*etiology, Adolescent ; Adult ; Age Factors ; Alcohol Drinking/epidemiology ; Carcinoma, Papillary/epidemiology ; Carcinoma, Papillary/pathology ; Female ; Humans ; Incidence ; Middle Aged ; Odds Ratio ; Retrospective Studies ; Risk Factors ; Smoking/epidemiology ; Surveys and Questionnaires ; Thyroid Neoplasms/epidemiology ; Thyroid Neoplasms/pathology ; Washington/epidemiology |
| مستخلص: | Both smoking and alcohol consumption may influence thyroid function, although the nature of these relations is not well understood. We examined the influence of tobacco and alcohol use on risk of papillary thyroid cancer in a population-based case-control study. Of 558 women with thyroid cancer diagnosed during 1988-1994 identified as eligible, 468 (83.9%) were interviewed; this analysis was restricted to women with papillary histology (N = 410). Controls (N = 574) were identified by random digit dialing, with a response proportion of 73.6%. We used logistic regression to calculate odds ratios (OR) and associated confidence intervals (CI) estimating the relative risk of papillary thyroid cancer associated with cigarette smoking and alcohol consumption. A history of ever having smoked more than 100 cigarettes was associated with a reduced risk of disease (OR = 0.7, 95% CI = 0.5-0.9). This reduction in risk was most evident in current smokers (OR = 0.5, 95% CI = 0.4-0.7). Women who reported that they had ever consumed 12 or more alcohol-containing drinks within a year were also at reduced risk (OR 0.7, 95% CI = 0.5-1.0). Similar to the association noted with smoking, the reduction in risk was primarily present among current alcohol consumers. The associations we observed, if not due to chance, may be related to actions of cigarette smoking and alcohol consumption that reduce thyroid cell proliferation through effects on thyroid stimulating hormone, estrogen, or other mechanisms. |
| معلومات مُعتمدة: | N01-CN-05230 United States CN NCI NIH HHS; R01 CA52656 United States CA NCI NIH HHS |
| تواريخ الأحداث: | Date Created: 20000101 Date Completed: 20000119 Latest Revision: 20190915 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1097/00001648-200001000-00011 |
| PMID: | 10615843 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1044-3983 |
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| DOI: | 10.1097/00001648-200001000-00011 |