دورية أكاديمية
[Antiradical and antioxidant properties of nonsteroidal anti-inflammatory agents--derivatives of pyridinecarboxylic acid].
| العنوان: | [Antiradical and antioxidant properties of nonsteroidal anti-inflammatory agents--derivatives of pyridinecarboxylic acid]. |
|---|---|
| عنوان ترانسليتريتد: | Antiradikal'nye i antiokislitel'nye svoĭstva nestroidnykh protivovospalitel'nykh sredstv--proizvodnykh piridinkarbonovykh kislot. |
| المؤلفون: | Gubskiĭ IuI; Institute of Pharmacology and Toxicology, Academy of Medical Sciences of Ukraine, Kyiv., Goriushko AG, Vistunova IE, Kurapova TN, Sachenko LG, Danilenko VF |
| المصدر: | Ukrains'kyi biokhimichnyi zhurnal (1999 ) [Ukr Biokhim Zh (1999)] 1999 Sep-Oct; Vol. 71 (5), pp. 85-9. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Nat︠s︡ionalʹna akademii︠a︡ nauk Ukraïny, Instytut biokhimiï im. O.V. Palladina Country of Publication: Ukraine NLM ID: 101657175 Publication Model: Print Cited Medium: Print NLM ISO Abbreviation: Ukr Biokhim Zh (1999) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kyïv : Nat︠s︡ionalʹna akademii︠a︡ nauk Ukraïny, Instytut biokhimiï im. O.V. Palladina, 1999-2013. |
| مواضيع طبية MeSH: | Anti-Inflammatory Agents, Non-Steroidal/*pharmacology , Antioxidants/*pharmacology , Carboxylic Acids/*pharmacology , Free Radical Scavengers/*pharmacology, Carboxylic Acids/chemistry ; Iron/metabolism ; Lipid Peroxidation ; Luminescent Measurements ; Mutation ; Pyridines/chemistry |
| مستخلص: | A number of pyridincarboxylic acid derivatives PV-1-4, 7 and emoxypine preparation antioxidative activity in yolk lipoprotein suspension was studied by a method of Fe(2+)-initiated biochemiluminescence. Lipid peroxidation in suspension was effectively inhibited by the studied compounds in various concentration ranges. PV 1, 3, 4, 7 inhibited lipid peroxidation at the concentrations 100-fold, then those of PV 2 and emoxypine. Antiradical activity of the studied compounds was demonstrated by their forming a complex with the stable diphenylpickrylhydrazyl radical. The effect of these compounds as antioxidants is discussed. |
| المشرفين على المادة: | 0 (Anti-Inflammatory Agents, Non-Steroidal) 0 (Antioxidants) 0 (Carboxylic Acids) 0 (Free Radical Scavengers) 0 (Pyridines) E1UOL152H7 (Iron) NH9L3PP67S (pyridine) |
| تواريخ الأحداث: | Date Created: 20000322 Date Completed: 20000531 Latest Revision: 20150803 |
| رمز التحديث: | 20240627 |
| PMID: | 10726316 |
| قاعدة البيانات: | MEDLINE |
| الوصف غير متاح. |