دورية أكاديمية
Tumor induction by Moloney sarcoma virus in athymic nude mice.
| العنوان: | Tumor induction by Moloney sarcoma virus in athymic nude mice. |
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| المؤلفون: | De Clercq E |
| المصدر: | Journal of the National Cancer Institute [J Natl Cancer Inst] 1975 Feb; Vol. 54 (2), pp. 473-7. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print Cited Medium: Print ISSN: 0027-8874 (Print) Linking ISSN: 00278874 NLM ISO Abbreviation: J Natl Cancer Inst Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2003-> : Cary, NC : Oxford University Press Original Publication: Bethesda, Md., U. S. Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health; Washington, for sale by the Supt. of Docs., U. S. Govt. Print. Off. |
| مواضيع طبية MeSH: | Mice, Nude* , Moloney murine leukemia virus*, Sarcoma 37/*transmission, Age Factors ; Animals ; Immunity, Cellular ; Mice ; Sarcoma 37/immunology ; Sarcoma 37/mortality ; T-Lymphocytes/immunology |
| مستخلص: | Athymic nude (nu/nu) mice, normal NMRI (plus/plus) mice, and nu/plus heterozygotes, inoculated at birth with the Moloney strain of murine sarcoma virus (M-MSV), did not differ either in tumor growth rate or incidence or in mortality due to tumor development; neither did nude (nu/nu) and normal NMRI mice inoculated with M-MSV at 30 days of age differ in the initial tumor growth rate. However, tumors induced in adult nude mice grew progressively and eventually killed the hosts, whereas tumors induced in adult normal NMRI mice completely regressed. These results indicated that thymus-dependent immunity, though not active in M-MSV tumor induction, determined whether the tumor, once formed, would regress or kill the host. |
| تواريخ الأحداث: | Date Created: 19750201 Date Completed: 19750510 Latest Revision: 20190509 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1093/jnci/54.2.473 |
| PMID: | 1078700 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0027-8874 |
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| DOI: | 10.1093/jnci/54.2.473 |