دورية أكاديمية
Glycosidase mechanisms.
| العنوان: | Glycosidase mechanisms. |
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| المؤلفون: | Rye CS; University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada., Withers SG |
| المصدر: | Current opinion in chemical biology [Curr Opin Chem Biol] 2000 Oct; Vol. 4 (5), pp. 573-80. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 9811312 Publication Model: Print Cited Medium: Print ISSN: 1367-5931 (Print) Linking ISSN: 13675931 NLM ISO Abbreviation: Curr Opin Chem Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Elsevier Original Publication: London : Current Biology Ltd., c1997- |
| مواضيع طبية MeSH: | Glycoside Hydrolases/*metabolism, Carbohydrate Sequence ; Enzyme Inhibitors/pharmacology ; Glycoside Hydrolases/antagonists & inhibitors ; Glycoside Hydrolases/chemistry ; Mutagenesis, Site-Directed |
| مستخلص: | Insights into glycosidase mechanisms have come from X-ray crystallographic studies on complexes with substrate analogs and inhibitors, representing all the intermediate species along the reaction coordinate. Site-directed mutagenesis continues to play a significant role in understanding mechanisms, but is also proving important in generating glycosidases of modified mechanism or specificity. |
| Number of References: | 60 |
| المشرفين على المادة: | 0 (Enzyme Inhibitors) EC 3.2.1.- (Glycoside Hydrolases) |
| تواريخ الأحداث: | Date Created: 20000928 Date Completed: 20001107 Latest Revision: 20191104 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/s1367-5931(00)00135-6 |
| PMID: | 11006547 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1367-5931 |
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| DOI: | 10.1016/s1367-5931(00)00135-6 |